Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"polymer micelles"”.
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Self-assembly of cross-linked polymer micelles into complex higher-order aggregates
The creation of complex polymer structures has been one of the major research topics over the last couple of decades. This work deals with the synthesis of (block co-)polymers, the creation of complex and stimuli-responsive aggregates by self-assembly, and the cross-linking of these structures. …
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Beta-Lapachone Nanotherapeutics for Lung Cancer Therapy
… Our objective was to develop β-lapachone polymer micelles for lung cancer treatment, in hopes of targeting tumors: 1) pharmacokinetically, through the use of a platform that will ensure drug stability, bioavailability, and targeted localized delivery; and 2) pharmacodynamically, through …
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Interaction Forces And Reaction Kinetics Of Ligand-Cell Receptor Systems Using Atomic Force Microscopy
… to study drug-delivery particles, in particular polymer micelles containing fluorescently labeled siRNA particles. In this study, we measured interaction forces and binding probability measurements between folate receptor functionalized cantilever and different substrates, as well as combined AFM …
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The benefit of precise chemical shift and concentration referencing in NMR applications
… for the analysis of interactions between polymer micelles and small molecules in solution, and (c) innovative studies of the release kinetics of small molecules from loaded porous-wall hollow glass microspheres”--Abstract, page iii.</p>
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Biocompatible polymeric nanoparticles for drug/DNA delivery using biologically friendly polymerisation processes
… explores the synthesis of several different polymeric nanostructures using reversible addition-fragmentation chain transfer (RAFT) polymerisation in both aqueous and ethanolic solutions.<br/><br/>A preface entailing an abstract, contents, common abbreviations and details of where this work …
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Degradable Polymers for the Controlled Delivery of Bioactive Small Molecules
… gasotransmitter-generating enzymes do. As such, polymeric delivery systems have been developed to extend the release of drugs, and in the case of gasotransmitters this more closely mimics in vivo production of HNO/H2S/RSSH. Polymeric systems have been employed to modulate gasotransmitter delivery …
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Synthesis, Properties, and Biology of Advanced H2S-Releasing Materials
… chemistry was utilized to prepare H2S-releasing polymers. Copolymers prepared using RAFT polymerization could be functionalized with SATOs with conversions > 99%, and these polymers released H2S on a similar timescale to our small molecule donors, confirming the viability of SATO formation as a …
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Design and Synthesis of Supramolecular Structures for the Controlled Release of Sulfur Signaling Species
… potential of H₂S. This work describes two polymer micelle systems for the controlled delivery of H₂S. The first system is based on H2S-releasing polymer amphiphiles with varying degrees of a plasticizing comonomer incorporated into the core-forming block. The glass transition temperature of …
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Hierarchical self-assembly of nanoparticles using reversible addition-fragmentation chain-transfer block copolymers
… quantum dots through the use of RAFT block copolymers have been investigated. The formation of cadmium selenide quantum dots within the core of tetrablock RAFT copolymers in three different solvents, dioxane, THF and DMF was investigated experimentally and computationally. It was determined …