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Showing 1 to 20 of 43 for “"polyhydroxyalkanoates"”.
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Biosynthesis of polyhydroxyalkanoates and their medical applications
… al., 2004). There are several factors that make polyhydroxyalkanoates (PHAs) excellent materials for use in TE, however, when used as scaffolds in bone TE, PHAs fail to actively bind to the living tissue by means of a biologically active apatite layer or meet the mechanical demands in …
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Biosynthesis of polyhydroxyalkanoates and its medical applications
Polyhydroxyalkanoates are polyesters of 3-hydroxyalkanoic acids produced by numerous Gram positive and Gram negative bacteria under nutrient limiting conditions. Once extracted, the PHAs exhibit a variety of properties from thermoplastic to flexible elastomeric nature. Biodegradability and …
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Nerve tissue engineering using blends of Polyhydroxyalkanoates
… aim of this project was to explore the use of Polyhydroxyalkanoates in nerve tissue engineering ultimately leading to the development of novel PHA-based nerve guidance conduits (NGCs). Production of the scl-PHA, P(3HB) and the mcl-PHA, P(3HO) through bacterial fermentation was performed to …
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Production of bioplastic precursors (polyhydroxyalkanoates) from macroalgae
… compounds of industrial interest, such as polyhydroxyalkanoates (PHAs), precursors of bioplastics, and thus contribute to reducing the impact of conventional plastics on the environment. However, due to the integral nature of the macroalgae structure, the accessibility of microorganisms to …
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Biosynthesis of polyhydroxyalkanoates for cardiac tissue engineering applications
As a result of the enormous clinical need, cardiac tissue engineering has become a prime focus of research within the field of tissue engineering. In this project, Poly(3- hydroxyoctanoate), P(3HO), a medium chain length (mcl-PHAs) biodegradable, biocompatible and elastomeric polyhydroxyalkanoate, …
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Production of Polyhydroxyalkanoates and their application for coronary stent development
… be addressed. Within this group of biomaterials Polyhydroxyalkanoates (PHAs), which are biopolyesters produced by bacteria, have a great potential in coronary stent development. They are biodegradable, non-toxic and biocompatible. PHAs have a broad range of properties, which can be tailored based …
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Biosynthesis of polyhydroxyalkanoates, their novel blends and composites for biomedical applications
Polyhydroxyalkanoates (PHAs) are a family of polyhydroxyesters of 3-, 4-, 5- and 6- hydroxyalkanoic acids produced by bacterial fermentation in a nutrient limiting conditions with excess carbon. They can be produced easily using renewable carbon sources. They are biodegradable and biocompatible in …
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Development of antibacterial Polyhydroxyalkanoates for their use in nerve tissue engineering
… In this perspective, this study utilized Polyhydroxyalkanoates (PHAs), linear bio-polyesters derived from bacterial fermentation process with biocompatible and biodegradable properties. PHAs are divided into two categories, according on the number of carbon atoms in a monomer unit: short …
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Production of Polyhydroxyalkanoates by Pseudomonas mendocina using vegetable oils and their characterisation
Synthesis of Polyhydroxyalkanoates (PHAs) by Pseudomonas mendocina, using different vegetable oils such as, coconut oil, groundnut oil, corn oil and olive oil, as the sole carbon source was investigated for the first time. The PHA yield obtained was compared with that obtained during the production …
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The Utilization of Activated Sludge Polyhydroxyalkanoates for the Production of Biodegradable Plastics
… operating procedures for the high production of polyhydroxyalkanoates (PHAs) by wastewater treatment (activated sludge) bacterial cultures. It was found that unbalanced growth conditions stimulated massive PHA production in activated sludge biomass. Operating conditions had a significant effect …
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Development of cardiac patches using medium chain length polyhydroxyalkanoates for cardiac tissue engineering
Medium chain length-PHAs (MCL-PHAs) have properties that make them exceptional for applications in cardiac tissue engineering. Cardiovascular diseases (CVD) are a major cause of death worldwide. Cardiac patches aim to facilitate the normal functioning of the heart muscle by providing repair and …
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The bacterial synthesis and characterisation of polyhydroxyalkanoates using waste plastics as carbon sources for novel applications
Polyhydroxyalkanoates (PHAs) are a group of biocompatible, environmentally neutral, biodegradable plastics that can be produced by bacteria. The structure of PHAs can be adapted for a wide range of applications, including biomaterials, 3D printing filaments, packaging and general household items. …
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Quroum sensing disruption and the use of short-chain fatty acids and polyhydroxyalkanoates to control luminescent vibriosis
… the application of short-chain fatty acids and polyhydroxyalkanoates. First, it was shown that formic, acetatic, propionic, butyric and valeric acid inhibit growth of luminescent vibrios in vitro in a pH-dependent way. Furthermore, the addition of 20 mM of the short-chain fatty acids to the …
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Systematic investigation of potential factors that affect the production costs of the bio-based and bio-degradable plastic polyhydroxyalkanoates (PHAs) by a costing analysis based on early process simulation
A transition is needed to shift the global economy to a more sustainable and clean economy to counteract the depletion of abiotic resources, generation of emissions and waste. Replacing petroleum plastics by bio-plastics is key to this move. This study identifies the bio-based and bio-degradable …
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Controlling dark fermentation of agro-industrial waste for valued organic acids production
… two specific applications were investigated: polyhydroxyalkanoates (PHA) production n and metal leaching. 1) Polyhydroxyalkanoates are biopolymers synthesized by several microorganisms as carbon and energy reserves in the event of carbon excess and nutrient deficiency. Industrial production of …
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Isolation of bacterial strains capable of efficient conversion of n-alkanes into value added products
… environmental strains might accumulate polyhydroxyalkanoates (PHAs) in their cytoplasm, which is a good candidate for biodegradable plastics. The gene that catalyzes PHA polymerization, phaC, was detected using PCR in some of the environmental strains. The strains of interest were …
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Biosynthesis and characterisation of polyhydroxyalkanoate biopolymers and their oligomers for circular economy
Polyhydroxyalkanoates (PHAs) are biodegradable bioplastics that can potentially replace non-biodegradable petroleum-based plastics. However, the high production cost of PHAs which is associated with the high cost of starting substrate extraction solvents limits its integration into large scale …
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