Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"polyhedrin"”.
-
Application of polyhedrin protein microparticles for in vivo vaccine and biologics delivery: a proof-of-concept study
… In this study, we assess the utilisation of polyhedrin protein based nanoparticles, for *in vivo* delivery of vaccines and biologics. The polyhedrin crystal phenomenon is naturally found within the life-cycle of insect viruses, whereby the encapsulation of mature viral particles by polyhedrin …
-
Regulation of late and very late gene expression in both lytic and persistent baculovirus infections
… the hyperexpression of the viral genes p10 and polyhedrin (polh), which are nonessential in vitro. While polyhedrin is a highly robust protein accumulating in the nucleus of virus-infected cells surrounding the virions and offering a degree of protection, the precise role of P10 is still …
-
The dual role of lef-2 in DNA replication and late gene expression during baculovirus-replication
… whereas very late gene expression (p10 and polyhedrin) was down regulated in the mutant. This evidence supports a dual role for lef-2 in DNA replication and very late gene expression. Further analysis of the region of lef-2 containing the mutation in VLD1 revealed 5 cysteine residues highly …
-
Baculovirus surface display of influenza virus haemagglutinin and its potential as a vaccine
… the benefits of using the FBU vector with the polyhedrin gene promoter in Tni Hi5 cells for producing HA incorporated into BV. Interestingly, use of the late p6.9 promoter did not result in increased levels of HA displayed in BV. Initial investigations also demonstrated the promise of RNAi …