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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 81 for “"polycaprolactone"”.
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Polycaprolactone nanowire surfaces as interfaces for cardiovascular applications
Cardiovascular disease is the leading killer of people worldwide. Current treatments include organ transplants, surgery, metabolic products and mechanical/synthetic implants. Of these, mechanical and synthetic implants are the most promising. However, rejection of cardiovascular implants continues …
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Encapsulation of nanomagnetite within polycaprolactone microspheres for bone replacement
… combining magnetite nanoparticles with polycaprolactone (PCL) to produce a material that can soften in response to the application of an alternating magnetic field. The magnetite nanoparticles were synthesized by a non-surfactant method and then emulsified with PCL. Particle size …
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Supercritical CO2 foamed biodegradable polymer blends of polycaprolactone and Mater-Bi.
… CO2 so blended with another polymer which is. Polycaprolactone is a biopolymer with potential of 4000% change in volume with CO2. Thus we investigate blends of Mater-Bi (MB) and polycaprolactone (PCL) foamed in supercritical CO2 using the batch process. Characterization of the foamed and …
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Tissue engineering of co-cultured skin substitutes using biocomposite membranes based on collagen and polycaprolactone
The preparation and characterisation of collagen: PCL, gelatin: PCL and gelatin/collagen:PCL biocomposites for manufacture of tissue engineered skin substitutes are reported. Films of collagen: PLC, gelatin: PCL (1:4, 1:8 and 1:20 w/w) and gelatin/collagen:PCL (1:8 and 1:20 w/w) biocomposites were …
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Design and Optimization of Angiogenic, Antibacterial Si-Zn-Hydroxyapatite for Use as Filler Particles in Polycaprolactone Nanocomposites
The development of synthetic biomaterials that replicate the biological functionality and mechanical resilience of native bone remains a central challenge in tissue engineering. Hydroxyapatite (HAp) is a widely used osteoconductive ceramic, but clinical outcomes can be limited by relatively low …
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Characterization and development of polycaprolactone (PCL)/montmorillonite (MMT)/hydroxapaptite (HA) nano-composites for fused deposition modelling (FDM) process
… Deposition Modelling (FDM) was investigated. The polycaprolactone (PCL) filled montmorillonite (MMT) and Hydroxyapaptite (HA) composites were prepared by melting and compounding using a single screw extruder. The mechanical properties were assessed by tensile, flexural and charpy impact tests …
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A novel osteochondral composite consisting of a self-assembling peptide hydrogel and 3D printed polycaprolactone scaffold : potential for articular cartilage repair
… with an interconnected porous 3D printed polycaprolactone (PCL) scaffold to create a novel osteochondral construct. The self-assembling peptide hydrogel has been shown to provide an environment that maintains chondrocyte phenotype and viability. Furthermore, the 3D scaffold fosters …
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Characterization of Environmentally Friendly Polymers: Amylopectin and Its Blends
… with biodegradable diluents including Polycaprolactone, Poly(DL-lactide-co-glycolide), and Poly(3- hydroxybutyric acid) were prepared. The physical properties and the thermodynamic characteristics of these blends were investigated using the Inverse Gas Chromatography (IGC) method. This …
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Tailoring electrospun nanofibers and electrosprayed nanoparticles to enhance cellular uptake of low bioavailability drugs
… polymer polyvinylpyrrolidone (PVP), and polycaprolactone (PCL) were used in the projects to produce nanomaterials using simple and straight forward techniques of electrospinning and electrospraying. In the first project, preparation, and characterization of PCL and PVP nanoparticles, …
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Design, characterization, and reinforcement of mineralized collagen-glycosaminoglycan scaffolds for orthopedic wound repair
… and subsequent characterization of a multi-scale polycaprolactone-collagen-glycosaminoglycan composite biomaterial for in vivo implantation and culture. In chapter 5 the polycaprolactone-collagen-glycosaminoglycan composite was then implanted in a subcritical mandibular ramus defect to affirm the …
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Design and development of desktop fiber and fabric manufacturing system for advanced materials
… 3 layer fiber with Polystyrene (PS) cladding, Polycaprolactone (PCL) layer, and PS core. These fibers were used for neural probing and cell scaffold.
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Dissolution and Biokinetics of PCL in Denitrification Systems
This thesis investigates the potential of polycaprolactone (PCL), a biodegradable polymer, as a sustainable solid-phase carbon source for wastewater denitrification. Laboratory experiments examined the effects of temperature, bead mass, solvent type, hydraulic retention time, and bead reuse on PCL …
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DEVELOPMENT OF BIO-ACTIVE FOOD PACKAGING FILMS
… packaging films was developed by melt blending polycaprolactone (PCL) with chitosan as carrier for grapefruit seed extract (GSE). The influence of molecular weight (MW) of chitosan on the blend was investigated. Lower MW chitosan accelerated the release of GSE that led to significant improvement …
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FABRICATION AND CHARACTERIZATION OF CELL-LADEN 3D PRINTED HYBRID SCAFFOLDS FOR ESOPHAGEAL TISSUE REPAIR
… of electrohydrodynamic jet printed (E-jetted) polycaprolactone (PCL) / Pluronic F127 (F127) fiber mesh, and a layer of electrohydrodynamic sprayed (E-sparyed) printed PCL film, has been applied for esophageal TE application. The E-jetted fiber mesh includes controlled and regular structure with …
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3D Printing Of A Biocompatible Scaffold And A Real-Time Imaging Window For Monitoring Rat Spinal Cord Regeneration
… visualization. Candidate scaffold materials- polycaprolactone (PCL), poly(lactic-co-glycolic acid) (PLGA), and silicone- were evaluated to balance mechanical compliance with biological performance. While PLGA exhibited favorable mechanical characteristics, PCL demonstrated superior …
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3D BIO-PRINTED SCAFFOLDS FOR TISSUE ENGINEERING AND REGENERATION: AN INVIVO EVALUATION WITH FURTHER OPTIMIZATION
… cell differentiation. Likewise, co-blending the polycaprolactone scaffold with Poly(lactic acid-co-ɛ-caprolactone) which would theoretically improve mechanical properties of the scaffold preliminarily supported cell proliferation and differentiation.
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Synthesis and Characterization of Branched Macromolecules for High Performance Elastomers, Fibers, and Films
… promise for a variety of applications. When a polycaprolactone triol was utilized as the B3 oligomer for the synthesis of highly branched polyurethane elastomers, the high degree of branching resulted in a completely amorphous soft segment, whereas the linear analogue with equivalent soft …
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Prozessentwicklung mit maßgeschneiderten rekombinanten Biokatalysatoren zur Synthese einer Bulk- und einer Feinchemikalie
… extraction was extended for the production of polycaprolactone by direct polymerization of ε-caprolactone in the organic compartment by means of lipase B yielding a polymer fraction having a degree of polymerization comparable to commercially available polycaprolactone. During experimental …
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Fabrication of Vascularized Renal Constructs
… of collagen vascular scaffolds molded off of polycaprolactone vascular corrosion casts of normal renal tissue. These novel vascular scaffolds can be endothelialized and incorporated into the existing renal hydrogel constructs. The vascular scaffolds support renal cell development and improve …
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