Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 69 for “"polyP"”.
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Polyp Detection in Colonoscopy Video
Colonoscopy is the only screening that can detect polyps in the colon that can mutate into colorectal cancer. The task of detecting polyps is a job done by the doctors themselves who perform the procedure. It often happens that polyps are not recognized for reasons such as fatigue of the doctor …
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Polyphosphate modulates hemostasis, thrombosis, and inflammation
Polyphosphate (polyP) is a linear polymer of inorganic phosphates that is secreted by activated platelets and is abundant in many pathogenic microorganisms. Our lab has recently shown that polyP from bacteria and human platelets play important roles in inflammation and coagulation in vitro and in …
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Polyphosphate Modification of Human Proteins and a New Mechanism for Regulating Super-Enhancer Activity
Inorganic polyphosphate (polyP) is an evolutionarily conserved linear polymer of orthophosphate that plays diverse regulatory roles across biological systems. Recent work has implicated that polyP modulates protein function through post-translational modification (PTM), which has gained increasing …
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Polyphosphate is a novel modulator of coagulation and inflammation and is a therapeutic target
… and thrombosis focuses on how inorganic polyphosphate (polyP) can mediate many of these novel amplification steps and many of the connections between coagulation and inflammation. Additionally, the multiple procoagulant and proinflammatory roles for polyP discovered in both mice and …
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Lysine Polyphosphate Modification Regulates Enzymatic and Signaling Functions in Eukaryotic and Bacterial Systems
Polyphosphate (polyP) is a highly conserved inorganic polymer involved in diverse regulatory processes across all domains of life. In bacteria, polyP is synthesized primarily by polyphosphate kinase 1 (PPK1) and deletion of the ppk1 gene results in significant alterations in cellular physiology and …
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Investigating the polyphosphate interactome with lysine- and histidine-rich proteins
Inorganic polyphosphate (polyP) is a biomolecule whose diverse functionality greatly belies its simple structure. PolyP is comprised of repeated inorganic phosphate units forming high energy phosphoanhydride linked polymers. Numerous studies have highlighted its vast portfolio of functions that …
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Mechanisms of polyphosphate degradation
… to investigate the mechanisms by which inorganic polyphosphate (polyP) is degraded in vivo. PolyP is a linear chain of phosphate moieties linked through high-energy phosphoanhydride bonds and can range in size from three-phosphates-long to thousands. Naturally, these molecular chains are stored in …
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Esforço reprodutivo de Mussismilia braziliensis (Verrill, 1868) (Cnidaria, Scleractinia, Mussidae) no complexo recifal dos Abrolhos, BA, Brasil
… estimated through fecundity (number of eggs per: polyp, cm 2, mesenteries and colony). A new staining method was used to ease identifying and counting eggs in the dissected polyps. The accuracy of the fecundity per gonad obtained through dissection was compared with histological analyses, and …
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Quantifying polyphosphate energy for modelling of polyphosphate accumulating organisms behaviour in anaerobic digestors
This study investigated the behaviour of polyphosphate accumulating organisms (PAOs) in linked activated sludge-anaerobic digestion (AS-AD) systems, with particular focus on quantifying polyphosphate (PolyP) energy and its role in PAO metabolism. The study was motivated by observed discrepancies …
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Tracking Inorganic Solids in Biological Enhanced Phosphorus Removal Wastewater Treatment Systems
… inorganic solids. This includes the formation of polyphosphate by phosphorus accumulating microorganisms (PAOs) and precipitation of inorganic minerals (e.g., struvite). Up until now, the only test that provides information on inorganic settleable or suspended solids (ISS) is the total solids test …
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Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population
… chronic rhinosinusitis (with or without nasal polyps). The main aim of treatment is to improve nasal symptoms by reducing or eliminating the nasal polyps and preventing polyp recurrence post-operatively. Our aims were to determine if the type of corticosteroid nasal spray used post operatively …
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Phosphorus physiology of the marine cyanobacterium Trichodesmium
… organic phosphorus (DOP) hydrolysis, and polyphosphate (polyP) biosynthesis and catabolism. These three pathways lay the foundation for the four chapters that make up the body of this thesis. Chapter two examines the relative importance of Pi and DOP in Trichodesmium in the Sargasso Sea by …
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Nitrate utilization as the final electron acceptor in a biological phosphorus removal system
… of the study were (1) to determine whether polyphosphate (polyP) microorganisms can use nitrate as the final electron acceptor, and (2) to evaluate and compare polyP accumulation in the biomass of the system using nitrate as the terminal electron acceptor to the system using oxygen as the …
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Regulation of Arachidonic Acid Pathway and Eosinophilic Inflammation in Chronic Rhinosinusitis/ Nasal Polyposis. Potential Role of Staphylococcus aureus Enterotoxins
… increased in chronic rhinosinusitis and nasal polyp subjects in contrast to EP1 and EP3, which were down regulated in the polyp group, suggesting a distinctive role of these receptors in the pathophysiology of nasal polyposis. Finally, based on our previous findings and parallel work of our …
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Phosphorus physiology of the marine cyanobacterium Trichodesmium
… organic phosphorus (DOP) hydrolysis, and polyphosphate (polyP) biosynthesis and catabolism. These three pathways lay the foundation for the four chapters that make up the body of this thesis. Chapter two examines the relative importance of Pi and DOP in Trichodesmium in the Sargasso Sea by …
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Variação de formas de crescimento de Montastraea cavernosa (Linnaeus, 1767) (Cnidaria, Anthozoa, Scleractinia): uma abordagem modular
… cavernosa using the arrangement and the size of polyps in the inner face of the colonial of 46 samples collected in Parcel das Paredes (BA) and João Pessoa (PB). Results showed that area of the polyps is partially explained by factors related to the spacing among them. These factors vary with the …
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Effects of synbiotics on cancer risk biomarkers
… and the genotoxic potential of FW in cancer and polyp subjects. Synbiotic consumption also reduced the proliferative activity in the colonic mucosa in polyp subjects. In both cancer and polyp subjects gene expression in the colonic mucosa was modulated in synbiotic consuming subjects. In this and …
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The Complex Interactions between Genetics and Environment: Diet, Inflammation and Intestinal Tumorigenesis
… lead to more rapid tumor progression, elevated polyp number and mass, as well as increased mortality, thus eliciting a detrimental impact on disease outcome, while one created from olive oil fails to induce an increase in polyp burden and reduce cancer severity in mice with genetic …
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Metagenomic characterization of Candidatatus Defluviicoccus tetraformis TFO71, a tetrad-forming organism, predominant in an anaerobic-aerobic membrane bioreactor with deteriorated biological phosphorus removal
… phosphatis (CAP) UW-1, a representative polyphosphate-accumulating organism (PAO), have PHA metabolism-related genes with high homology, but TFO71 has unique genes for PHA synthesis, gene regulation, and granule management. We further discovered genes encoding DTFO polyphosphate (polyP) …
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