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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"poly(lactic acid) (PLA)"”.
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Study of poly (l-lactic acid)/poly (d-lactic acid) stereocomplex as nucleating agent for poly (l- lactic acid) crystallization
Poly (lactic acid) (PLA) is a biodegradable polymer with good renewability and processability. However, it has some drawbacks. The Poly (lactic acid) (PLA) stereocomplex formed via the interaction between optical isomers Poly (L-lactic acid) (PLLA) and Poly (D-lactic acid) (PDLA), provides …
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Structure-Property Evaluation of the Dielectric Properties of Radar Absorbing Materials in Free Space
… EM radiation. For this work, several commercial polymer matrices were used with 4 additives, i.e., graphite flake (GF), graphite powder (GP), iron powder (CIP), and carbon black (CB), at varying loading levels to understand the structure-property relationships that affect dielectric properties in …
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Uniform double wall microspheres/microcapsules for protein delivery
Biodegradable polymer devices have been utilized as a means to deliver drugs in a controlled and less invasive manner. Poly (lactide-co-glycolide) (PLG) and poly (lactic acid) (PLA) microparticles such as double-wall/single-wall microspheres and microcapsules were heavily investigated for …
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Synthetic vascular materials via a vaporization of sacrificial component (VaSC) approach
… (VaSC). The chosen sacrificial material, poly(lactic acid) (PLA), can be easily incorporated into composites and undergoes a solid-to-gas transition at ca. 280 oC, which allows for the extraction of the gaseous product from the composite leaving hollow spaces in the matrix. The fabrication …
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Synthesis and evaluation of novel polymer modifiers for biodegradable polymers
The effects of ester plasticizers and copolymers on the mechanical properties of the natural biodegradable polymers, poly(3-hydroxybutyrate) [PHB] and poly(lactic acid) [PLA] have been studied after subjecting to melt processing conditions. Ester plasticizers were synthesized from citric, tartaric …
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Production of biodegradable poly lactic acid from pineapple industry wastewater by lactobacillus casei fermentation
… of this study is to produce biodegradable poly lactic acid (PLA) from pineapple industry waste water by Lactobacillus casei. The L. caseiwas cultivated with a medium containing extracted glucose for 24 h. The optimisation of cultural conditions (temperature, pH, inoculum size, nitrogen …
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DRUG ELUTING TISSUE ENGINEERED VASCULAR GRAFTS
… secondary to a phenomenon called Intimal Hyperplasia (IH). We have performed previous animal studies using 2mm TEVG in rabbits and 5mm TEVG in sheep which had restenosis rates secondary to IH of 70% and 60% respectively. IH is secondary to an inflammatory response after implantation resulting …
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Controlled Release System for Localized and Sustained Drug Delivery Applications
… a specific period of time. Chitosan is a natural polysaccharide that has many characteristics to be used for biomedical applications. In the last two decades, there have been a considerable number of studies affirming that chitosan could be used for pharmaceutical applications. However, chitosan …
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Bioresorbable Electrospun Tissue Scaffolds of Poly(ethylene glycol-b-lactide) Copolymers for Bone Tissue Engineering
Poly(α-hydroxy esters) are a class of biocompatible resorbable polyesters including poly(lactic acid) (PLA) and poly(glycolic acid) (PGA) that are FDA-approved for clinical use. Preliminary tissue culture studies have demonstrated that these poly(α-hydroxy esters) support bone tissue development …
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Bimetallic Main-Group Catalysts for the Synthesis of Advanced Biocompatible, Biodegradable, and Sustainable Polymers
… and industrial sectors. Among these, poly(lactic acid) (PLA) and its copolymers are especially notable for their biodegradability, sustainability, and tunable chemical and physical properties. This dissertation presents a systematic investigation into the synthesis of PLA and its …
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Designing High Performing Durable Bio-Based Coatings for Packaging Applications
… packaging applications using renewable biopolymers. These include cellulose, extracted from plants, and chitin, sourced from mushrooms and food waste like crustacean exoskeletons. These natural polymers can form strong, high-performance films but are limited by moisture sensitivity and …
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Antimicrobial PLA and Calcium Phosphate Coatings and Thin Film Composites for Implants Applications
Implant-related infections after the insertion of biomedical implants are still prevalent, and the current treatment methodology requires the use of large doses of antibiotics systemically. Large doses can lead to a number of side effects including antibiotic resistance and adverse effects on the …
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Characterization of natural fibre reinforced biodegradable composities
… strength of natural fibres make them a good replacement for synthetic fibre such as glass in fibre reinforced plastics (FRP). Green and ecofriendly source of these fibres offer less reliance on oil sources. However, their moisture uptake ability, low thermal stability and quality variations are …
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STRUCTURALLY SUPPORTED CELL-LADEN SCAFFOLDS FOR BONE TISSUE REGENERATION
… construct capable of possible in vivo implantation.</p> <p>In Chapter 2 of this work, osteoblast-like human osteosarcoma cells (Saos-2) were encapsulated within gelatin methacrylate (GelMA) hydrogels and the effect of the hydrogel density on cellular morphology and mineralization was …
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Uniform biodegradable microparticle systems for protein delivery
… protein therapeutics’ application. Biodegradable polymer devices have been utilized as a means to deliver drugs in a controlled and less invasive manner. Poly(lactide-co-glycolide) (PLG) and poly(lactic acid) (PLA) microparticles such as double-wall/monolithic microspheres and microcapsules have …
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Bioinspired microvascular self-healing in polymers and composites
… and ultimately mechanical stasis. In polymers, autonomous release of reactive chemistries from ruptured vasculature offers distinct advantages over prior self-healing approaches; largely, the capacity to achieve macro-scale fracture recovery over multiple damage cycles by replenishment …
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Optically pure D (-) lactic acid biosynthesis from diverse renewable biomass: microbial strain development and bioprocess analysis
Lactic acid is an important platform chemical that has long history and wide applications in food, polymer, pharmaceutics and cosmetic industries. Lactic acid has two optical isomers; namely D-lactic acid and L-lactic acid. Racemic mixture of lactic acid are usually used as preservatives and …
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Elucidation of weak organic acid resistance mechanisms in non-Saccharomyces yeast: a case study of Zygosaccharomyces parabailii and Kluyveromyces marxianus
… cell factories is a promising option to replace the fossil based petrochemical refinery. Different bacteria, algae and yeasts are currently used as microbial hosts, and their number is predicted to increase over next years. Minimum nutritional requirements and robustness have made yeasts a …
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Controlling the alignment and degradation of 3D printed poly-L-lactic acid for redesigned coronary stents
… commercially successful material for this is polylactic acid (PLA), although, numerous challenges remain before the stent’s wider implantation. As a material, PLA is widely used within fused filament fabrication (FFF) 3D printing. FFF could be a viable technique for manufacturing …
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