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Showing 1 to 12 of 12 for “"poly(N-isopropyl acrylamide)"”.
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Poly (N-isopropyl acrylamide) brush topography: relationship to film collapse and protein adsorption
Made available in DSpace on 2013-02-03T19:18:31Z (GMT). No. of bitstreams: 2 Byung-Chan_Choi.pdf: 1830922 bytes, checksum: 742937613b4c5a0c78c70ef10e902f1a (MD5) license.txt: 4064 bytes, checksum: 53cdea897122dbf51517ac552aeb19e9 (MD5)
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Advancing fast relaxation imaging to determine protein stability and folding kinetics on poly(n-isopropyl acrylamide) films
… have reported the use of the thermo-responsive polymer PNIPAM to capture and release cells or proteins for medical purposes; however, this assumes that PNIPAM does not perturb the stability of biomolecules. Previous analytical and spectroscopic techniques have not been able to confirm this …
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POLY(N-ISOPROPYL ACRYLAMIDE)-COATED SURFACES: INVESTIGATION OF CYTOTOXICITY WITH MAMMALIAN CELLS AND THE MECHANISM OF CELL DETACHMENT
… such as those generated from stimulus-responsive polymers. Stimulus-responsive polymers undergo a physical or chemical change when a stimulus is applied. One such material is poly(N-isopropyl acrylamide), (pNIPAM), which undergoes a conformation change in a physiologically relevant temperature …
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Topographically and Mechanically Tunable PNIPAM Scaffolds
Poly(N-isopropyl-acrylamide) (PNIPAM) is a thermoresponsive polymer with a wide range of biological applications, including drug delivery, biosensing, and tissue engineering. The tunability of the structural and mechanical properties of PNIPAM makes it particularly at- tractive in emulating cell …
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High-throughput platforms for investigating bioadhesion and cell migration
… thermally tunable cell adhesion and release from poly(N-isopropyl acrylamide) brushes. Large format polymer gradients were used to screen grafting densities and substrate chemistries that alter both cell adhesion and rapid, reversible release by switching temperature. The study demonstrated the …
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Immobilization of Inorganic Nanoparticles on Responsive Polymer Brushes
Exploitation of well defined responsive polymer brushes for direct and controlled immobilization of metal/semiconductor nanoparticles on macroscopic surfaces has been demonstrated. The employed approach offers the possibility of the organization of a variety of inorganic nanoparticles by …
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Assessment of the biocompatibility, stability, and suitability of novel thermoresponsive films for the rapid generation of cellular constructs
Stimuli responsive polymers (SRP) are of great interest in the bioengineering community due to their use in applications such as drug delivery and tissue engineering. One example of an SRP is poly(N-isopropyl acrylamide) or pNIPAM. This SRP has the capability of changing its conformation with a …
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Metal-polymer nanoparticulate systems for externally-controlled delivery
Metal-polymer nanocomposites consisting of gold nanorods and temperature-responsive hydrogel nanoparticulates were investigated for use in externally-controlled drug delivery systems. Several different thermo-responsive hydrogels including poly(N-isopropyl acrylamide) (PNIPAAm) and …
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A study of inter- and intramolecular interactions through neutron compton scattering and low temperature matrix isolation infrared spectroscopy
… in momentum distributions in a solution of poly-N-isopropyl acrylamide (pNIPAAm) passing through a temperature-induced phase change, deuterated polymer/ solvent mixtures were studied on the VESUVIO instrument at the ISIS RAL facility, and the analysis of that data is presented. pNIPAAm and …
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Introduction of a thermo-sensitive non-polar species into polyelectrolyte multilayer capsules for drug delivery
The layer-by-layer assembly (LBL) of polyelectrolytes has been extensively studied for the preparation of ultrathin films due to the versatility of the build-up process. The control of the permeability of these layers is particularly important as there are potential drug delivery applications. …
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Design, fabrication, and application of stimuli-responsive hydrogel actuators
… trisbipyridine (Ru(bpy)32+) monomer within a poly acrylamide (PAAm) gel, modified to provide a flexible chemistry for UV-curable, self-oscillating Belousov-Zhabotinsky (BZ) gels. Then, inspired by the photosensitizing capability of Ru(bpy)32+ from the first project, we successfully used …
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Towards greener stationary phases : thermoresponsive and carbonaceous chromatographic supports
Polymers which are sensitive towards external physical, chemical and electrical stimuli are termed as ‘intelligent materials’ and are widely used in medical and engineering applications. Presently, polymers which can undergo a physical change when heat is applied at a certain temperature (cloud …