Global ETD Search
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Showing 1 to 7 of 7 for “"podoplanin"”.
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The functional characterisation of murine CLEC-2 and analysis of the expression of its ligand, podoplanin, on macrophages
Includes abstract. Includes bibliographical references (p. 109-125).
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Λεμφαδενική μετάσταση σε luminal-A καρκίνο μαστού: συσχέτιση με βιοδείκτες και ο ρόλος τους ως προγνωστικοί παράγοντες
… συσχέτιση μεταξύ της έκφρασης της Ποδοπλανίνης (PodoplaninBREASTCA) και του σταδίου της νόσου (rho = .43, p = .019). Επιπλέον το PodoplaninBREASTCA συσχετίστηκε σημαντικά με τη λεμφαγγειακή πυκνότητα (LYMPHO MVD) (rho = .57, p < .001). Παρόλα αυτά δε φάνηκε στατιστική σημαντικότητα μεταξύ …
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Immunhistologische Charakterisierung experimenteller Lymphangiome der Maus
… und Prox1 für Lymphendothelzellen sowie gegen Podoplanin, Meca32 und VEGFR-2, ein vaskulärer Wachstumsfaktorrezeptor, wurde die Häm- und Lymphangiogenese untersucht. Dabei zeigte sich, dass Blut- und Lymphgefäße kontinuierlich vom Diaphragma ausgehend in die Tumoren vorgedrungen waren. …
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The ageing hair follicle environment. Alterations in the female scalp and mesenchyme with age.
… changes in collagen organisation, reduced podoplanin (PDPN) and increased versican (VCAN) expression. Hyaluronic acid synthase 2 (HAS2) was highly expressed throughout the scalp. Matrix Metallopeptidase 1 (MMP1) and Metallopeptidase inhibitor 1 (TIMP1), cyclin-dependent kinase inhibitor 2A …
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The role of lymph node-derived lymphatic endothelial cells in immune modulation in the tumour microenvironment
… knockout models, a role for lymphatic expressed Podoplanin in DC interactions and migration. Prolonged physical interactions were further found to facilitate antigen transfer from ovalbumin-loaded LECs to DCs yet inhibit DC priming of T-cells, with DCs found capable of acquiring TDLN-LEC archived …
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Immunotoxin Monotherapy and Combinatorial Therapy With Immune Checkpoint Inhibitors for Malignant Brain Tumors
… proteins in glioblastomas. NZ-1-IT reacts with podoplanin (PDPN), a protein that has a high expression in glioblastomas and medulloblastomas. </p><p>In vitro cytotoxicity data shows that both ITs effectively inhibited protein synthesis in a variety of epitope-expressing glioblastoma and …
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Risk-Factor Induced Changes In The Breast Microenvironment Facilitate Inflammatory Breast Cancer Progression and Lymphovascular Invasion
<p>Inflammatory breast cancer (IBC) is a rapidly progressing, rare and highly lethal form of breast cancer. IBC is a clinical diagnosis, requiring >1/3 involvement on the affected breast and/or skin by erythema, and disease onset of < 6 months. The clinical symptoms of IBC vary in severity and …