Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"pluripotency factor Nanog"”.
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Cryo-electron microscopy studies of pluripotency factor Nanog
… rise to cell types from all lineages, known as pluripotency. Culture of ES cells in vitro requires addition of signalling molecules such as LIF to block differentiation signals and maintain self-renewal. At the transcriptional level, self-renewal is governed by the ‘network of pluripotency’; a …
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Regulation of amnion induction during the human formative pluripotency transition
… amniotic ectoderm (AME) segregation and explore pluripotency transitions modulate AME competency. Single cell RNA-sequencing reveals AME specification and confirms that the in vitro derived AME cells closely resemble embryo AME rather than TE. Unexpectedly, TE potential persists during early …
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Activin/Nodal Signalling Controls the Epigenome and Epitranscriptome of Human Pluripotent Stem Cells
… elucidating the signalling pathways regulating pluripotency and differentiation, our mechanistic understanding of the downstream regulations is still incomplete. Moreover, studies aimed at clarifying these aspects are severely impeded by the lack of efficient methods to conditionally modulate …