Global ETD Search
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Showing 1 to 3 of 3 for “"plexins"”.
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Plxna4 and its role in neuronal survival in the developing zebrafish hindbrain
Plexins are a family of transmembrane proteins that bind Semaphorin ligands, and are known to function in axon guidance. In embryonic zebrafish, I find that plxna4 is expressed widely in the nervous system early in development, and localizes to the hindbrain as neurogenesis and differentiation …
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Sema-1a Reverse Signaling Promotes Midline Crossing In Response To Secreted Semaphorins
… neurons Sema-1a acts independently of Plexins to inhibit Rho and promote attraction to the midline. These findings suggest that Sema-1a reverse signaling can elicit distinct axonal responses depending on differential engagement of ligands and signaling effectors.
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Effekte der Klasse-3 Semaphorine auf die Entwicklung und Progression maligner Hirntumoren
Neuropiline gehören zu den endothelialen Oberflächenrezeptoren und agieren als Rezeptoren für angiogene Faktoren aus der Familie der VEGF-Familie (vascular endothelial growth factor). Daneben spielen sie als Rezeptoren für Faktoren der Axon-Orientierung aus der Klasse-3-Semaphorin-Subfamilie eine …