Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 88 for “"pleural"”.
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Diagnóstico de derrame pleural maligno mediante la concentración de homocisteína en líquido pleural
Introducción: los derrames pleurales malignos (DPMs) son exudados causados por la presencia de tumores en la pleura (cáncer). La concentración de homocisteína en líquido pleural (HCY) puede ser útil para el diagnóstico de DPM. Objetivos: los objetivos de este estudio fueron evaluar la concentración …
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Stromal interactions in pleural mesothelioma
Pleural mesothelioma (PM) is a devastating malignancy primarily related to past asbestos exposure. There are no curative options, and 1-year survival stands currently at just 40%. The genomic landscape in mesothelioma is dominated by loss of function of tumour suppressor genes rather than …
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Utilidad del ácido láctico en líquido pleural para la clasificación de la gravedad del derrame pleural paraneumónico en pediatría
Introducción: La indicación de drenaje pleural en derrame pleural paraneumónico (DPPN) sigue siendo controvertida. El pH del líquido pleural (LP) es ampliamente utilizado como indicador de la necesidad de drenaje pleural. Nuestra hipótesis es que el lactato de LP tiene una buena correlación con el …
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The Significance of Cleaved Cytokeratin 18 in Pleural effusion
목적 : 흉막 유출의 발생과정에서 상피세포의 사멸이 역할을 하는 것으로 알려져 있다. 흉수 및 흉막 조직에서 이를 평가하여 원인 질환의 감별에 있어서의 유용성 및 임상적 의의를 평가해 보고자 한다. 대상 및 방법 : 총 79명의 환자를 대상으로 하였다. 흉수의 원인 질환으로는 폐암 24예, 결핵 28예, 폐렴 15예, 여출액 12예였다. 환자의 흉수와 혈액에서 세포분석 및 생화학적 검사를 시행하였고 상피세포의 사멸을 평가하기 위하여 caspase-cleaved cytokeratin 18의 특이적 항원인 M30에 대한 항체를 …
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Zirconium-based Metal-Organic Frameworks for Pleural Mesothelioma Therapy
… studies to improve the treatment of malignant pleural mesothelioma, an incurable cancer with a survival time of only one year after diagnosis. Mesothelioma is mainly caused by exposure to mining asbestos, a natural fibre widely used in building constructions. This untreatable cancer is …
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The significance of the EGFR pathway in malignant pleural mesothelioma
… MTOR and COX2 are up regulated in malignant pleural mesothelioma (MPM). In this study we aimed to determine the expression of Lipoxygenase enzymes (LOX), absence of PTEN protein expression and the cytotoxic effect of EGFR, MTOR and COX2 inhibitors in MPM.Materials and …
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The study of the role of mast cells in malignant pleural effusion
… We found mast cells in mouse and human malignant pleural effusions, and studied their functions. Mouse adenocarcinomas competent of malignant effusions potently chemoattracted and subsequently degranulated mast cells in the thorax by releasing chemokine ligand 2 and osteopontin, respectively. Mast …
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Differently charged polypeptides and their impact on peritoneal and pleural postoperative adhesion formation
… polypeptides and their impact on peritoneal and pleural postoperative adhesion formation Abstract: Abdominal adhesions are formed after previous peritoneal traumas where previous surgery poses the most frequent cause. An increasing number of clinical complications due to adhesions have been …
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Pleural effusion and human immunodefeciency virus infection in adult Zambians : a clinical and laboratory study
… carried out on 80 adult Zambian patients with pleural effusion in order to determine common features and to establish any association with human immunodeficiency virus (HIV) infection at the University Teaching Hospital, Lusaka. No such a study had been done before in Zambia (before or after …
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Cullin 4B Ubiquitin Ligase Is Important for Cell Survival and Regulates TGF-β1 Expression in Pleural Mesothelioma
… was associated with worse outcomes of pleural mesothelioma (PM) patients, while the overexpression of its paralog CUL4A was not associated with clinical outcomes. Here, the work aimed to identify the distinct roles of CUL4B and CUL4A in PM using an siRNA approach in PM cell lines (ACC …
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Caracterización epidemiológica, clínica y paraclínica de niños con derrame paraneumónico y empiema pleural en Bogotá en 2018
… de la neumonía bacteriana son el derrame pleural paraneumónico y el empiema pleural, y su incidencia ha venido en aumento en los últimos años. El propósito del presente estudio fue hacer una caracterización clínica y epidemiológica completa de pacientes con esta entidad con el fin de tener …
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A Flow Cytometric Analysis of Immunocyte Populations in Peripheral Blood and Pleural Effusions of Patients with Cancer
… on paired samples of peripheral blood (PB) and pleural effusions (PE) of patients with metastatic malignancies. The purpose of these analyses was to test the hypothesis that there are significant differences in the distribution of immunocyte populations in the PE compared to that of the PB.</p> …
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Aetiology and presentation of childhood pleural infections in the post-pneumococcal conjugate vaccine era in South Africa
Complications of respiratory infections include pleural effusion (PE), associated with a high morbidity. Differentiating between PE caused by bacterial infections and Mycobacterium tuberculosis (TB) in endemic areas is difficult in children, impacting treatment. We investigated the aetiology of PE …
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