Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"platelet factor 4"”.
-
Regulation of Myeloid Leukemia Cells by Platelet Factor 4
… efficacy of the megakaryocyte-derived chemokine platelet factor 4 (PF4) to inhibit LSC proliferation and alter the course of AML disease progression in syngeneic mouse models and human AML cells. We found that PF4 preferentially acts on LSCs via low-density lipoprotein receptor (LDLR) to inhibit …
-
Pyridoxylation of the essential lysines in the heparin-binding site of bovine platelet factor 4.
The lysine residues of bovine platelet factor 4 essential to heparin-binding activity have been determined. The protein was labelled by pyridoxal 5$\sp\prime$-phosphate and reduced by sodium borohydride. Three moles of lysine residues are labelled per mole of platelet factor 4. This resulting …
-
Biokompatibilitätsuntersuchungen an Originaldialysatoren in einem In-vitro-Dialyse-Rezirkulationsmodell unter besonderer Berücksichtigung von Faktor XIIa-C1-Inhibitor, einem Marker für die Aktivierung des Kontaktphasensystems
… Thrombin-antithrombin complex (TAT), platelet loss, platelet factor 4 and C5a were measured to detect activation of the coagulation cascade, platelet activation and complement activation.The contact system is generally believed to be the main trigger of the coagulation cascade during …
-
The Influence of Resistance Training on Primary Hemostatic Responses
… in helping to reduce the hyperaggragability of platelets following acute strenuous exercise. The present investigation was designed to explore the effects of an acute resistance exercise test (AERET) and recovery on the primary hemostatic system in both resistance trained and untrained …
-
Optimization of primary endothelial culture methods and assessment of cell signaling pathways in the context of inflammation
… data regarding how angiostatic cues like Platelet Factor 4 can modulate angiogenesis signaling pathways. Our results from working with both types of endothelial cell systems provide insight into potential methods for establishing specialized microvasculature for engineered tissues, both in …
-
Einfluss von hyperthermen Oberflächen auf Humanblut
… regard to red blood cells, white blood cells, platelets and hematocrit, no statistically significant temperature-dependent difference could be shown at temperatures up to 45°C. Yet, respecting the conditions of the dummies and the blank sample, hemoglobin as well as PF4 (platelet factor 4) seem …
-
Expression of angiogenic growth factors in laryngeal carcinoma
… for 29 of these proteins in nodal tissue; MMP9, platelet factor 4 and Serpin E1 did not show an increase until T4. Thirty-one of the 32 proteins were expressed at a higher level in T3/T4 tumour tissue compared with the corresponding node, and 29/32 proteins were expressed more highly in T1 tumour …
-
The Requirement for Viable Platelets in the Coagulation of Heparinized Blood
… blood or plasma samples containing normal platelets were compared with ACT’s of heparinized samples containing non-viable or abnormally functional platelets. The non-viable platelets were prepared by freeze/thawing, and the abnormally functional platelets resulted from the addition of …
-
New approaches to improve the cord blood unit hematopoietic progenitor cell content
… cell content of cord blood units. In this study, factors that may improve the selection and quality of cord blood collections for banking were identified. In 167 consecutive cord blood units collected from healthy full-term neonates and processed at a national cord blood bank, mean platelet volume …