Global ETD Search

Plasmacytoid Dendritic Cell-Mediated Humoral Autoimmunity

Dorta-Estremera, Stephanie M, Ph.D.2016

… is characterized by the breakdown of B cell immune tolerance to self-antigens and consequent production of pathogenic autoantibodies. Plasmacytoid dendritic cells (pDCs), a potent type I interferon (IFN-I) producer, have been linked to the pathogenesis of systemic lupus erythematosus …

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Respiratory viruses promote glycolysis the critical role of metabolism in human plasmacytoid dendritic cell antiviral responses

Bajwa, GaganTexas Woman's University2015

twu Repository record for Respiratory viruses promote glycolysis the critical role of metabolism in human plasmacytoid dendritic cell antiviral responses (opens in a new tab)

On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets

Lood, ChristianSection of Rheumatology, Dept of Clinical Sciences, Lund2012

… patients have an impaired ability to clear dying cells which leads to the exposure of several nuclear antigens which might break self tolerance. Autoantibodies directed against the nuclear antigens will form large immune complexes (ICs) which are central in the immunopathogenesis of SLE. Through …

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Deciphering pre-leukaemic dysregulation caused by mutant C/EBPα at the level of the single cell

Qureshi, MoosaUniversity of Cambridge2020

… by mutant C/EBPα at the level of the single cell Moosa Rashid Qureshi C/EBPα is an ideal candidate to explore pre-leukaemic dysregulation of transcriptional networks because it is a significant player in normal myelopoiesis, it interacts with other transcription factors (TFs) in lineage …

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Effects of commonly used antiviral vaccines on human plasmacytoid dendritic cells

Nussbaum, BenediktUniversität Ulm

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Regulation of human granzyme B-producing plasmacytoid dendritic cells by viral stimuli

Panitz, Verena MichaelaUniversität Ulm

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Molecular signatures underlying the tumourigenic transformation in a CEBPA mutated model of leukaemia

Zarocsinceva, MarijaUniversity of Cambridge2024

… system could provide insight into early cellular and molecular mechanism of leukaemia development. In this work a cellular model of CEBPA mutated leukaemia was generated focusing on a C-terminal N321D mutation of CEBPA that was previously reported to cause AML in mouse models. The mutated …

cambridge Repository record for Molecular signatures underlying the tumourigenic transformation in a CEBPA mutated model of leukaemia (opens in a new tab)

Studies on the Interaction between Porcine Plasmacytoid Dendritic Cells and Porcine Reproductive and Respiratory Syndrome Virus

Calzada-Nova, GabrielaUniversity of Illinois at Urbana-Champaign2015

… of ineffective, non-immunizing antibodies and a cell-mediated immune response that is weak and protracted. The later was proposed to be result of a lack of adequate IFN-<;t production by the host, which is necessary to promote the development of protective anti-viral cell mediated immunity. …

uiuc Repository record for Studies on the Interaction between Porcine Plasmacytoid Dendritic Cells and Porcine Reproductive and Respiratory Syndrome Virus (opens in a new tab)