Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"placebo controlled trial"”.
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Effects of Lees from Brown Rice on Waist Circumference and Metabolic Parameters in Type 2 Diabetes: A Randomized, Double-blinded, Placebo-controlled Trial
… This study is a randomized, double-blinded, placebo-controlled study, scheduled for 12 weeks. Thirty subjects were randomly assigned to receive either a dietary fiber supplement from lees of brown rice (LB) or a mixed-grain based dietary product (MG). The body weight, waist circumference, …
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Blood and Lumbar Fluid Biomarker Changes in Patients with HIV-Associated Neurocognitive Impairment Treated with Lithium: Analysis from a Randomised Placebo-Controlled Trial
… obtained from participants in a randomized placebo-controlled trial of lithium in ART-treated individuals with moderate or severe HAND. We assayed markers at baseline and 24 weeks across several pathways hypothesized to be affected by HIV, inflammation, or degeneration. Investigated …
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The Effect of Melatonin Upon Post-Acute Withdrawal Among Males in a Residential Treatment Program (M-Paws): A Randomized, Double-Blind, Placebo Controlled Trial
… was a single-center, randomized, double-blind, placebo-controlled, parallel group trial of 28 days. Participants were randomized to melatonin (5 mg) or placebo and instructed to administer the intervention nightly at bedtime. Primary self-reported outcome measures of severity of anxiety, …
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Role of Vitamin D receptor and vitamin D binding protein restriction fragment length polymorphisms in determining dose response to vitamin D: a randomized double blind placebo controlled trial
… in older subjects) - a double blind randomized placebo-controlled trial that enrolled 160 healthy Caucasian postmenopausal women, with vitamin D insufficiency (mean serum 25OHD 15.6 ng/ml) recruited during winter and followed for one year. The subjects were randomly assigned to placebo, vitamin …
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The impact of isoniazid preventative therapy and antiretroviral therapy on tuberculosis (TB) in HIV-infected children in a high TB incidence setting
… using data from a prospective, double-blinded placebo controlled trial of INH versus placebo in HIV-infected children in Cape Town, South Africa.
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The immunomodulatory role of prednisone in patients with HIV-associated tuberculosis and assessment of its impact on lung function outcome
… do this using data collected during the PredART trial. This randomized, double-blind, placebo-controlled trial showed that a 28-day course of prophylactic prednisone in adult patients identified as being at high risk for paradoxical TB-IRIS reduced the incidence of paradoxical TB-IRIS by 30%, …
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Melatonin-micronutrients Osteopenia Treatment Study (MOTS): A translational study assessing the effects of melatonin, strontium citrate, vitamin D3 and vitamin K2 on bone density, bone turnover markers and health-related quality of life in postmenopausal osteopenic women following a one-year double-blind randomized placebo-controlled trial and on osteoblast-osteoclast co-cultures
… study was designed as a one-year double-blind, placebo-controlled randomized trial, which assessed the effects of nightly MSDK supplementation containing 5 mg melatonin, 450 mg strontium citrate, 2000 IU vitamin D<sub>3 </sub>and 60 mcg vitamin K<sub>2</sub> (MK7) on bone mineral density (BMD), …
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Omega-3 fatty acid supplementation to improve body composition and perceived stress in collegiate athletes.
… n-3 supplementation. Design: In this randomized, placebo-controlled trial, 17 Baylor University track and field athletes participated in an 8-week study. The experiment group (n=9) received 4.0 g of FO n-3 daily, while the placebo group (n=8) received 4.0 g of coconut oil. Baseline and post-study …
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Optimising therapeutic strategies for chronic rhinosinusitis
… control. We have therefore in a double-blind placebo controlled trial (Chapter 4) evaluated the effect of this initial induction with oral steroids on subsequent sequential intranasal therapy. Perhaps, however, more crucially we have for the first time comprehensively addressed the safety of …
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The Impact of Cognition on Treatment Adherence in Comorbid Bipolar Disorder and Cocaine Dependence
… enrolled in a 10 week randomized, double-blind, placebo controlled trial of lamotrigine. Baseline performance on the Stroop Color and Word Test and the Rey Auditory Verbal Learning Test were examined for their effect on retention, appointment attendance, medication adherence, and return of …
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A randomised controlled trial of N-acetylcysteine in the management of anti-tuberculosis drug-induced liver injury
… Methods: We conducted a randomized double-blind placebo-controlled trial of intravenous NAC in adult hospitalized participants with AT-DILI. Primary endpoint was time to ALT < 100 U/L; secondary endpoints included length of hospital stay and 8-week mortality. We described outcomes of ATT …
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The effects of clobazam and lorazepam on patient's psychomotor performance and anxiety
… outpatients in a randomized double-blind, placebo- controlled trial comparing the 1,5 benzodiazepine clobazam (10 mg (two times a day) to lorazepam (1 mg two times a day). Carefully selected tests were administered pre-treatment and at 2 and 9 days after treatment. Compliance was checked by …
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The effects of Omega-3, Omega-6 Polyunsaturated Fatty Acids (PUFAs) and Vitamin E on patients with the remitting-relapsing (RR) form of Multiple Sclerosis (MS) in Cyprus
… in multiple sclerosis patients, however clinical trials remain inconclusive due to a plethora of reasons. In this randomized, double blinded, placebo controlled trial aiming to provide concrete conclusions for the role of PUFAs and vitamins A and E (both gamma (γ) and alpha (α)) in multiple …
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A biscuit fortified with iron, iodine and B-carotene as a strategy to address micronutrient deficiencies in primary school children
… and compared with 113 controls, in a randomised placebo-controlled trial. To enhance the absorption of iron a vitamin C-fortified cold drink was given together with the biscuit. Anthropometric status, cognitive function and morbidity were assessed as secondary outcomes. The 12-month intervention …
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¿CHIOS MASTIC GUM FROM PISTACIA LENTISCUS AS A MODULATOR OF INFLAMMATION AND INTESTINAL BARRIER FUNCTION: AN IN VITRO AND CLINICAL INVESTIGATION.¿
… patients with IBD. A randomized, double-blind, placebo-controlled trial involved 31 adults diagnosed with ulcerative colitis or Crohn's disease who were in clinical remission yet exhibited subclinical inflammation. Standardized questionnaires and faecal biomarkers (calprotectin, zonulin), were …
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The pathophysiology of chronic subdural haematoma and the role of the dexamethasone
… This work was performed alongside the Dex-CSDH trial, a randomised, placebo-controlled trial of the potent anti-inflammatory dexamethasone. Blinded interim results of the trial are discussed, but the main focus are the scientific, mechanistic sub-studies. A method for detecting dexamethasone in …
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A cross-sectional study of the association between cognitive impairment and haemoglobin levels in HIV-infected South Africans established on antiretroviral therapy
… count results performed as part of a randomised placebo controlled trial that evaluated the efficacy of lithium carbonate for the treatment of HIV associated neurocognitive disorders. Results The majority of our participants were female (87%) with a mean age of 37 ±7.78 years. Participants were …
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Cost-effectiveness of nebulised ipratropium as adjunctive therapy in acute asthma
… of acute asthma were studied in a double-blind, placebo-controlled trial in which they received a standard therapeutic regimen of continuous intravenous aminophylline, 4-hourly fenoterol nebulisation, intravenous methylprednisolone 125mg 12-hourly, and, every four hours, either nebulised saline …
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The role of acute phosphate supplementation in endothelium-dependent and -independent vasodilation
… years old) were exposed to phosphate (PHOS) and placebo (PLAC) conditions over two experimental days (one each visit) in a within-subjects, randomized, double-blinded, placebo-controlled trial. Subjects drank a liquid containing 1200 mg of phosphorus or a placebo. FMD tests were performed pre- …
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Aspects of functional constipation - a trial of an opioid antagonist as a treatment and an investigation of the colonic microbiota associated with the illness
… of this research were to conduct a randomised, placebo-controlled trial investigating an opiate antagonist (Naloxone - Nalcol™) on symptom relief in FC and secondly to describe the colonic microbiota in FC and determine the effect of Nalcol™ on it. MATERIAL AND METHODS The trial consisted of; a …
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