Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"pituitary adenoma"”.
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The neurocognitive consequences of non-functioning pituitary adenoma and its treatment
Patients with pituitary adenoma often report problems with cognitive function. However, the current literature is inconsistent on the types of cognitive deficits that patients experience. Chapter 1 of this thesis reviews the current literature and the questions that are still unanswered concerning …
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The Association between Sleep Quality and Cognitive Function in Patients with Nonfunctioning Pituitary Adenoma?s
… in particular), and (c) patients with pituitary disease (PD) experience hormonal dysregulation, impaired quality of sleep, and particular patterns of cognitive dysfunction. However, the current study is the first to examine (using objective measures of sleep quality) whether there are …
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Central disorders of thyroid function: clinical, radiological and genetic phenotyping
… of ultrasensitive TSH assays and improvements in pituitary imaging studies, diagnosing and uncovering the aetiology of both central hyper- and hypo-thyroidism remains challenging in many cases. This thesis adds data to the existing literature generated from studies in large cohorts of patients …
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Optimisation of molecular imaging using 11C-methionine PET in the detection of pituitary adenomas
Decision-making in pituitary disease is critically dependent on high-quality imaging of the sella and parasellar region. Magnetic resonance imaging (MRI) is the investigation of choice, and for the majority of patients combined T1 and T2 weighted sequences provide the information required to allow …
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Prolactinoma gigante: relato de caso
… Magnetic resonance imaging (MRI) of the pituitary-hypothalamus showed a solid-cystic expansive lesion in the sellar and suprasellar region, compressing the optic chiasm, measuring 4.0 x 4.2 x 3.0 cm. Laboratory evaluation showed hyperprolactinemia [>470 ng/dL (4.04-15.2)] and central …
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Ion channels and electrical excitability in native murine anterior pituitary corticotrophs
As a central component of the hypothalamic-pituitary-adrenal (HPA) axis, the anterior pituitary corticotrophs play an important role in the regulation of HPA axis function and the neuroendocrine response to stress. Pituitary corticotrophs integrate stress-induced stimulatory signals (CRH and AVP) …
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Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy
… was explored for intraoperative delineation of adenoma and healthy pituitary tissue. A novel rigid multispectral endoscope was developed, preliminary technical characterisation of this device was performed, and a clinical pilot study was planned. With continuation of this work as outlined at the …