Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"pit-1"”.
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Regulation of Pituitary Genes by the Transcription Factor, Pit-1, in the Domestic Turkey (A Turkey is NOT a Feathered Rat)
The transcription factor, Pit-1, is involved in the transcriptional regulation of the mammalian prolactin (Prl), growth hormone (GH) and thyroid stimulating hormone b-subunit genes (TSHb) as well as its own gene. The role of Pit-1 in avian species is unknown. Three turkey (t) Pit-1 isoforms have …
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Functional characterisation of ANKH mutants in the pathology of CPPDD and CMD
… ENPP1 activity, expression of ENPP1, TNAP and PIT-1 to characterise mutant biochemical effects in the pathogenesis of CPPDD and CMD. Our data showed the P5L mutation delayed cell membrane localization but once the protein was recruited into the membrane it functioned to increase ePPi, …
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Restoration of Prime Farmland Disturbed by Mineral Sand Mining in the Upper Coastal Plain of Virginia
… Experiments were established on two mine pits representing two likely pit closure scenarios; regrading the surface with unprocessed subsoil (Pit 1) or filling to the surface with processed material (Pit 3). To evaluate topsoil replacement vs. organic amendment, each pit was split into two …
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Transcriptional regulation of the prolactin gene in turkeys
Poor reproductive performance by turkey hens compared with chickens is partially due to the early cessation of egg production associated with the onset of incubation behavior. Prolactin (Prl) is involved in the induction and maintenance of incubation behavior in birds, and understanding the …
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Resolving the Role of POU1F1 in Human Growth Hormone Locus Activation
… HSI and HSII contains the predominant pituitary somatotrope-specific hGH-N activation function of the LCR. This activity was attributed primarily to POU1F1 (Pit-1) elements at HSI, as linkage to HSI was sufficient for properly regulated hGH-N expression in transgenic mice, but …
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THE ROLE OF ENDOTHELIAL CELLS IN VASCULAR CALCIFICATION
… dependent on calcium influx without influencing Pit-1 expression. During the first days of high-Pi treatment ECs change their morphology from cobblestone to spindle shape acquiring motility, as demonstrated by the 14% increased closure in the scratch wound healing test. EndMT master genes such as …
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The Mapping of Transcription Factor Binding Sites in the Turkey Prolactin Gene
… these methods are labor intensive. The anterior pituitary hormone prolactin (PRL) is involved in the onset of incubation in the turkey hen. Levels of circulating PRL and PRL mRNA are 10X greater in photostimulated hens than in photorefractory hens, 20X greater in laying hens, and 100X greater in …
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Protein factors and 5' flanking sequences involved in the expression of the mouse myelin basic protein gene.
… activating transcription factor 2 (ATF-2), the pituitary specific positive transcription factor 1 (Pit-1) or general transcription factor 2i, the E2F family transcription factor, the PASK protein and two of the clones were identified as c-jun. One clone, however, remains unidentified and this …