Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"pimavanserin"”.
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The Serotonin (5-HT) 5-HT2A Receptor is a Priority Target to Reduce Impulsive Action in Substance Use Disorders: Preclinical Evidence
… FDA-approved 5-HT2AR antagonist/inverse agonist pimavanserin (Nuplazid®) as a therapeutic to forestall relapse vulnerability in cocaine use disorder (CUD). Pimavanserin suppressed impulsive action while baseline levels of impulsive action predicted the effectiveness of pimavanserin to suppress …
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Strategies to Identify Therapeutic Opportunities in the Treatment of Addictive Disorders
… receptor (5-HT2AR) antagonist/inverse agonist pimavanserin and 5-HT2CR agonist lorcaserin used alone or in combination demonstrate efficacy in suppressing measures of binge eating. Pharmacological studies further show that activation of the 5-HT2CR may suppress binge eating by decreasing the …