Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"phytoestrogen"”.
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Breast Cancer Progression and Phytoestrogen Interactions with Estrogen Receptors
… studies suggests that dietary consumption of phytoestrogens may modulate disease progression. This study hypothesises that the interaction between some phytoestrogens (present in the pre-diagnosis diet or in the new diet adopted by breast cancer patients) and specific ER isoforms displayed in …
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A Novel Phytoestrogen that Acts as an Agonist for Human Estrogen Receptors.
… However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with ERs, and therefore effect the estrogenic response, may …
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The Phytoestrogen Genistein Induces Thymic and Immune Changes: A Human Health Concern
Use of soy-based infant formulas has aroused concern due to potential estrogenic effects of the soy isoflavones genistein and daidzein. Here we show that subcutaneous genistein injections in ovariectomized adult mice produced dose-responsive decreases in thymic weight of up to 80%. Genistein's …
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The Effects of Estrogen Receptor -Alpha, Estrogen and Phytoestrogen on Global Myocardial Ischemia -Reperfusion Injury
… mice (Control). The effects of estrogen and phytoestrogen were investigated in 6 control mice (Control). The effects of estrogen and phytoestrogen were investigated in 6 groups of female rats. One group was a sham-operated control for ovariectomy and fed a diet free of phytoestrogen (SHAM …
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Activation of proestrogens from hops by human intestinal bacteria: conversion of isoxanthohumol into the potent phytoestrogen 8-prenylnaringenin
… (8-PN) would be the most potent phytoestrogen currently known. Therefore, hop extracts are now marketed to relief menopausal complaints but efficiency varies greatly among individuals. As variability in biological activity was also noted for other phytoestrogens and related with …
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Evaluation of a modified food frequency questionnaire to measure lignans in Australian men and women
Phytoestrogens are plant compounds that possess estrogenic and biological properties that have been postulated to protect against chronic diseases. Isoflavonoids and lignans are two main classes of phytoestrogen that have been investigated for their estrogenic efficacy and occurrence in the human …
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Effects of dietary calcium, phytoestrogen rich diets and estrogen on intestinal calcium transport proteins, egg and eggshell quality in maturing layer hens / Ali Asghar Saki.
… and shell quality are significantly reduced by phytoestrogen. It is recommended that the concentration of phytoestrogen in poultry diets be investigated in more detail as it may act as an anti-nutritive factor and affect metabolism and productivity.
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Quantitative analysis and metabonomic study of phytoestrogens in Africans
Phytoestrogens have been widely studied in various parts of the world. However, little is known about the availability, absorption, metabolism and its biochemical effects in Africans. The principal aim of this research was to investigate the phytoestrogen content in six African staple foods, their …
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Factors Influencing Early Embryonic Development in the Pig
Results from the phytoestrogen study indicate that the phytoestrogens, daidzein and genistein at concentrations (0, 10 nM, 30 nM, 100 nM, 300 nM, 1 muM and 3 muM) had no developmental effect on pig embryos, however pig embryos cultured with 3 muM daidzein may improve blastocyst formation over …
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Effects of exercise and phytoestrogens on white adipose tissue health in estrogen deficient rodents
… and WAT inflammation. Exercise and dietary phytoestrogen interventions can improve metabolic and WAT health in menopausal women and OVX rodents. The studies in this dissertation were designed to investigate the visceral WAT underlying mechanisms to determine how voluntary wheel running …
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Genistein-Induced Potentiation Effect on Glucose-Stimulated Insulin Secretion (GSIS) in INS-1 β-cells
… long-term exposure. Genistein, a isoflavonoid phytoestrogen isolated from soy bean seed and having tyrosin kinase inhibition activity, had a potentiation effect on GSIS (glucose-stimulated insulin secretion) in pancreatic INS-1 beta cells. Although the potentiation effect was glucose-dependent, …
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Estrogen Inducible Serpin, Proteinase Inhibitor 9, in Immunosurveillance and Apoptosis
The phytoestrogen genistein has attracted a great deal of recent interest. In MCF-7 cells, we find that 10 nM genistein induces PI-9 as effectively as saturating E2, and genistein treated MCF-7 cells are resistant to NK cell mediated cytotoxicity. In ERalphaHA cells, the dose response curves for …
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Pengaruh ekstrak air daun katu (Sauropus androgynus (L.) Merr) terhadap panjang fase diestrus dan proliferasi epitel vagina mencit (Mus musculus L.) betina premenopause
… The complaints can be overcome by giving phytoestrogen. Katu leaf contains isoflavone that has the potential as a phytoestrogen. Therefore, this study aimed to determine the effect of water extract of leaf valve (Sauropus androgynus (L.) Merr) to the length of diestrus phase and …
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Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles
… conversion of daidzein, a major isoflavone phytoestrogen in soybean, in the gut of some humans and many animal species. Previous studies indicate that isoflavones and their metabolites can affect endogenous estradiol production, action, and metabolism via several mechanisms, which could in …
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Factors affecting estrogen excretion in dairy heifers
… in feces and urine due to increased dietary phytoestrogen content. Ten Holstein heifers were randomly assigned to treatment sequence in a two-period crossover design. Dietary treatments consisted of grass or red clover hay, and necessary supplements. Feces and urine samples were collected and …
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Analyse molekularer Mechanismen der ERα- und ERβ-vermittelten Wirkung spezifischer Liganden und des Phytoestrogens Genistein
… Wirkungsweisen gewebespezifische Einflüsse des Phytoestrogens Genistein (Gen) näher charakterisiert werden. Es konnte gezeigt werden, dass nach einer subkutanen Applikation der knochenprotektive Einfluss von Gen mit dem von Estradiol (E2) vergleichbar ist, durch die Kombination mit Bewegung …
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Efeito do relaxamento induzido por diosgenina em artéria mesentérica de rato após administração de 17-β estradiol.
… researchers have attempted, in studies with phytoestrogens, an alternative to impro ve the treatment of this illness, since hormone replacement therapy harms to patients with breast or uterine cancer. Among various existing phytoestrogens tried to assess the cardiovascular activity of …
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Estrogenic Effects of Genistein in Ovariectomized Gilts
… by exposure to high doses of the soybean phytoestrogen genistein.
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Measurement and risk assessment of endocrine disruptors present in sport supplements
… two categories: plant based compounds called phytoestrogens and a group of natural and synthetic estrogens (endogenoushormones and xenoestrogens). The exposure and risks connected with these two groups of estrogenic compounds were assessed separately (Chapter 5). Subsequently,the influence of …
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Physiological consequences of exposure to heat stress and the mycotoxin zearalenone
… problematic for swine, as it is a potent phytoestrogen. As such, it can reduce productivity by disrupting reproductive processes. Although these topics are disparate, the overarching goal of this work is to improve agricultural animal productivity during periods of heat stress. Overall, …
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