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Showing 1 to 1 of 1 for “"physiologie-basierte Pharmacokinetic (PBPK)"”.
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Integrating nonlinear mixed effects and physiologically–based modeling approaches for the analysis of repeated measurement studies
… studies, the characterization of the drug's pharmacokinetics (PK) is an important aspect, since the PK is assumed to strongly impact safety and efficacy. To this end, drug concentrations are measured repeatedly over time in a study population. The objectives of such studies are to describe …