Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 66 for “"photosensitizers"”.
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METAL NANOSTRUCTURES-ENHANCED AIE-BASED PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY
… and various cancers. However, traditional photosensitizers are suffering from aggregation-caused quenching (ACQ) effect, due to π-π stacking. The ACQ leads to weak fluorescence at aggregated state, low photostability, and less ROS generation ability. There are two main strategies to enhance …
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The investigation of kairomones and photosensitizers affecting Liriomyza bryoniae (Diptera, Agromyzidae) /
… friendly, non-toxic photoinsecticides (photosensitizers). Knowing that tomato leafminers locate and recognize the suitable host-plants by plant-emitted volatiles, such plant-origin compounds (kairomones) could be used for insects’ attraction to the bait with photosensitizer. The aim of …
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THE DEVELOPMENT OF SELECTIVE PHOTOSENSITIZERS TO TARGET PATHOGENIC T CELLS AND PREVENT GRAFT-VERSUS-HOST DISEASE
… work presented here, we have created a series of photosensitizers with the ability to target oxidative phosphorylation (OXPHOS) in pathogenic and malignant T cells. The photosensitizers are also potent stimulators of P-glycoprotein (P-gp). Enhanced P-gp activity promotes the efficient removal of …
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Dental caries prophylaxis with photosensitizers (experimental, laboratory and clinical studies) // Профилактика на зъбния кариес с фотосенсибилизатори (експериментални, лабораторни и клинични изследвания)
[EN] Dental caries is a social, multietiological bacterially-mediated disease with significant consequences for the oral and the overall health of the human population. Diseases related to microbial biofilms are one of the most prevalent bacterial diseases in humans. The process of destruction of …
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Method For Determination Of Singlet Oxygen Quantum Yields For New Fluorene-based Photosensitizers In Aqueous Media For The Advancement Of Photodynamic Therapy
… developed in the laboratory, to screen potential photosensitizers in aqueous media.The singlet oxygen quantum yield is a quantitative measurement of the efficiency in which photosensitizers are able to use energy, in the form of light, to convert oxygen in the ground state to the reactive species …
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Synthesis of novel asymmetrically substituted phthalocyanines
… are among the more promising second generation photosensitizers for photodynamic therapy. Our research group has consistently shown that the more amphiphilic of these compounds display improved biological properties as photosensitizers for photodynamic therapy. However, synthetic approaches …
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Development of Iridium Based Photosensitizer for Potent Photoreductants and Photocatalytic Application
… the development of iridium based organometallic photosensitizers which function as potent photoreductants for photoredox catalysis. Chapter 1 describes the basic concepts of photosensitizers in photocatalysis and strategies to modify the photophysical and electrochemical properties via ligand …
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Investigation into the potential of methylene blue and its derivatives to be used in the photodynamic therapy of non-pigmented and pigmented cells
… melanin for light absorption. Second-generation photosensitizers have tended to be porphyrin-based molecules, many of which have reached various stages of clinical trial. Of non porphyrin-based compounds, the cationic dye, methylene blue (MB), used traditionally as a nuclear stain in histology, …
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Persistence of Bacteroides ovatus under simulated sunlight irradiation
… were determined in the presence of exogenous photosensitizers and salinity up to 39.5 parts per thousand at 27oC. UVB was found to be important for B.ovatus decay, averaging a four log10 of decay over 6 h of exposure without the presence of extracellular photosensitizers. The addition of …
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Design, Synthesis and Spectroscopy of Highly Absorptive Chromophores Based on the Bis(tridentate)metal-ethyne-(porphinato)metal Molecular Framework for Solar Energy Conversion
<p>Highly absorptive photosensitizers are in great demand for solar energy conversion applications that include dye-sensitized solar cells, photoelectrochemical cells, and photo-redox catalysis. In this dissertation, the design, synthesis and spectroscopy of a series of different highly absorptive …
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Photoactivatable Organic and Inorganic Nanoparticles in Cancer Therapeutics and Biosensing
… and can be repeated as needed. Different photosensitizers such as porphyrines, chlorophylls, and dyes have been used in PDT to treat various cancers, skin diseases, aging and sun-damaged skin. These second generation sensitizers have yielded reduced skin sensitivity and improved extinction …
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Nanoclusters for Cancer Therapy: Assesment of Their Reactive Oxygen Species Generation and Stability
… that uses light to activate drugs known as photosensitizers inside the body. Nanoclusters can act as photosensitizers because they absorb light and use this energy to generate reactive oxygen species, resulting in targeted cancer cell death. To be an effective photosensitizer, clusters must …
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Quantum chemical investigation of electron delocalization patterns during photoexcitation in Fischer carbene complexes: a theoretical study
… and excited states of various organometallic photosensitizers are investigated using FALDI in order to probe the degree of electron delocalization present in metal-to-ligand charge transfer states.
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Synthesis, Characterization, and Evaluation of Novel BODIPY Dyes With Theranostic Applications
… The utilization of fluorescent BODIPYs as photosensitizers for photodynamic therapy, and as boron delivery agents for boron neutron capture therapy offers promise as theranostic agents. Additionally, BODIPY derivatives that absorb and emit in the near-IR regions of the electromagnetic …
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Ultrafast extreme ultraviolet spectroscopy of transition metal dithiolate coordination complexes
… for the development of catalysts and photosensitizers using earth-abundant transition metals. The cobalt dithiolene complex, [Co(bdt)2]- (bdt = 1,2-benzendithiolate), is primarily known for its ligand-noninnocence and participation in the catalytic production of hydrogen. After …
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Synthesis of Phenothiazinium Derivatives
… active singlet oxygen that kills cancer cells. Photosensitizers currently used in PDT are of low quantum yield and require high energy radiation, normally laser. Therefore there is always need for more effective PDT drugs. In this project we synthesized new derivatives of phenothiazinium for …
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Photodynamic therapy against multidrug-resistant oral strains of Candida spp
… protocols and new procedures based on new photosensitizers and/or different light radiation sources. In fact, this thesis is aimed at three main objectives: (i) First, describe and compare the clinical effectiveness of the main PDT therapies already used against Candida infection; (ii) …
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