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Showing 1 to 1 of 1 for “"phosphorothioate modifications"”.
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Development of functional DNA-based sensors and investigations into their mechanism
… investigated in Chapter 4, through systematic phosphorothioate (PS) modifications on the backbone of the DNAzyme. Kinetic assays with the PS modified bases have shown that there are specific bases on the enzyme strand which are important for activity mainly in the presence of Pb2+. The …