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Showing 1 to 6 of 6 for “"phosphodiesterase 3B"”.

  1. Hormonal regulation of phosphodiesterase 3B in adipocytes

    Lindh, RebeckaLund University, Medical Faculty, Department of Experimental Medical Science2007

    … induced activation of the cAMP degrading enzyme phosphodiesterase (PDE) 3B in adipocytes is important for insulin mediated inhibition of lipolysis. The aim of this thesis was to contribute with knowledge on the acute activation of PDE3B in response to insulin and catecholamines in adipocytes. The …

    lund Repository record

  2. THE ROLE OF PHOSPHODIESTERASE 3B IN CAMP-MEDIATED REGULATION OF INSULIN SECRETION

    Jones, HelenaMedical Faculty, Lund University2007

    … to investigate the role of ?-cell cAMP-degrading phosphodiesterase 3B (PDE3B) in the regulation of insulin secretion and whole body energy homeostasis. The specific aims were (i) to study the physiological importance of well-regulated ?-cell-cAMP levels for insulin release and whole body energy …

    lund Repository record

  3. Studies in beta cells and adipocytes in the context of obesity and T2D - focusing on PDE3B, OPN and SCFAs

    Heimann, EmiliaInsulin Signal Transduction2014

    … regard to the regulation of cyclic nucleotide phosphodiesterase 3B (PDE3B) in pancreatic β-cells. We show that PDE3B is activated in response to glucose, insulin and forskolin, which is coupled to a decrease, no apparent change or an increase in total phosphorylation of the enzyme in rat …

    lund Repository record

  4. The role of supplementary calcium in submaximal exercise and endurance performance.

    Jawadwala, RehanaUniversity of Central Lancashire2012

    … of cyclic Adenosine Monophosphate (cAMP) and phosphodiesterase 3B (PDE 3B) has been implicated in the relationship between calcium and lipolysis (Xue et al., 2001). The objective of the series of studies presented in this thesis was to investigate the ergogenicity of supplementary calcium in …

    cent-lancashire Repository record

  5. Rola fosfodiesterazy 3B w regulacji sekrecji insuliny u szczura (Rattus norvegicus Berkenhout)

    Zywert, Agnieszka2016

    amu-pl

  6. Functional validation of human rare missense variants associated with body fat distribution and cardiometabolic risk

    Dong, LiangUniversity of Cambridge2021

    … p.N150H), CALCRL (p.L87P), PLIN1 (p.L90P) and PDE3B (p.R783X) which were associated with a favourable body fat distribution and with protection from cardiometabolic disease, while a variant in gene PNPLA2 (p.N252K) was associated with an adverse phenotype (1). To understand the roles of these …

    cambridge Repository record