Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"phosphatidylinositol (3,4)-bisphosphate"”.
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A screen for phosphatidylinositol 3,4-bisphosphate and other 3-phosphoinositide effector proteins
… and metabolism via their primary lipid product phosphatidylinositol 3,4,5- trisphosphate (PtdIns(3,4,5)P3) and a metabolite of this, phosphatidylinositol 3,4- bisphosphate (PtdIns(3,4)P2). Many effector proteins for PtdIns(3,4,5)P3 are well recognised but by contrast, few molecular targets for …
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The 5' inositol phosphatase SHIP2 regulates EGF-elicited protrusion in MTLn3 cells
… that catalyzes the dephosphorylation of phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P 3) to phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) as well as the dephosphorylation of phosphatidylinositol 4,5- bisphosphate (PI(4,5)P 2). PI(3,4,5)P 3 and P][(4,5)P 2 are two major …
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Molecular mechanisms of Sorting nexin-9 in membrane triggered actin polymerisation
… SNX9 are able to integrate inter- actions with phosphatidylinositol phosphates (PIPs) at membranes, and membrane curvature sensing to trigger actin polymerisation via the Arp2/3 complex. While membrane binding is key in in vitro purified reconstitutions of actin polymerisation, the lipid …
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Role of trans-Golgi network vesicles in mitochondrial fusion
… fusion site. A screen examining the set of phosphatidylinositol phosphate (PIP) species as potential regulators of mitochondrial morphology uncovered the localization of phosphatidylinositol (3,4)-bisphosphate [PI(3,4)P2] in close proximity to the mitochondrial network. PI(3,4)P2 is produced …