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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 52 for “"phosphatidylethanolamine"”.
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The Effect of Seven Carcinogens on Phosphatidylcholine and Phosphatidylethanolamine Metabolism in Larvae of the Indian-Meal Moth
<p>Alterations of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) metabolism were investigated in the larvae of Plodia interouncte11a (Indian-meal moth) receiving diets containing seven different carcinogense The fatty acid composition of PC and PE as well as the radioactive …
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Analysis of gamma secretase regulation by phosphatidylethanolamine using mammalian and Drosophila melanogaster in vitro and in vivo model systems
… proteolytic processing of this protein. As phosphatidylethanolamine (PE), an important regulator of diverse cell processes, accounts for the majority of PL I focused on the regulation of APP proteolyisis by this particular PL. For this purpose I utilized Drosophila melanogaster and mammalian …
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Lateral organization and dynamics of phospholipids in membrane
… and dansyl-labeled phosphatidylcholine, phosphatidylethanolamine, or phosphatidic acid. However, another integral membrane protein, D-$\beta$-hydroxybutyrate dehydrogenase (BDH), reorganized the phospholipids in the bilayer into a nonrandom distribution. Although the enzyme has a specific …
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Structural effects of neutral lipids on the divalent cation-induced interactions of phosphatidylserine - containing bilayers
… were again obtained with PC, and also with phosphatidylethanolamine (PE). A combination of X-ray diffraction, thin-layer chromatography, density gradient centrifugation and freeze-fracture electron microscopy, used in conjunction with an osmotic stress technique, showed that (i) -30 mole % …
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Identification and quantification of lipid metabolites in cotton fibers: Reconciliation with metabolic pathway predictions from DNA databases.
… predominant lipid class in fiber cells, while phosphatidylethanolamine, phosphatidylinositol and digalactosyldiacylglycerol were also prevalent. An unusually high amount of phosphatidic acid was observed in frozen cotton fibers. Phospholipase D activity assays revealed that this enzyme readily …
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Effect of Lipid Modification on Transformation - Associated Properties and Viral Membrane Assembly
… polarization was correlated with a higher phosphatidylethanolamine/phosphatidylcholine ratio in the transformed cell plasma membrane, as well as differences in the fatty acid composition.
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Studies on the mode of action of the pyrithione biocides
… by the presence of EDTA and extracellular phosphatidylethanolamine. ZnPT was also neutralised by the presence of cysteine. Molecular modelling studies indicated direct chemical interactions between the pyrithiones and cysteine and the pyrithiones and phosphatidylethanolamine. Oxygen …
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Characterization of the lipid composition of washed and percoll gradient centrifuged epididymal mouse sperm.
… compositions of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) were characterized in washed non-capacitated (WS), washed capacitated (WCS), and Percoll gradient centrifuged (PGC) capacitated (PGCS) epididymal mouse sperm. Fatty acid methyl esters were generated from PC and PE by …
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Interactions of Inorganic Mercury and Inorganic Cadmium with Biomimetic and Complex Biological Membranes and their Influence on Membrane Packing and Size
… ether hydrolysis of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) plasmalogens. Cd2+-induced rigidity of anionic membranes results in a stabilization of the gel phase and a suppression of the Tm of membranes composed of phosphatidic acid (PA), cardiolipin (CL), phosphatidylserine …
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Role of High Molecular Weight Hyaluronan in Ultraviolet B Light-Induced Transformation
… in resistance to keratinocyte tumors, a HMW HA phosphatidylethanolamine (HA-PE) formulation that penetrates skin and accumulates as coats around keratinocytes was prepared. The tumor resistance properties of the HA-PE formulation were tested in a mouse model of UVB-induced KC (Hr-/- Ptch+/-). …
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On the mechanisms of substrate translocation by the ABC transporter MsbA
… for achieving significant rates of ATP-dependent phosphatidylethanolamine transport. In contrast, Lipid-A transport is active with the input of ATP only. Although chemical proton gradient does not stimulate Lipid-A transport, the membrane potential does enhance the transport reaction. Finally, …
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Regulation of n-3 PUFA biosynthesis in proliferating and differentiated PC12 pheochromocytoma cells
… docosapentaenoic acid (DPA, 22:5n-3) and DHA in phosphatidylethanolamine (EPG) and phosphatidylserine (SPG) glycerophospholipids (GPL) via the elongation/desaturation pathway following alpha-linolenic acid (ALA, 18:3n-3) supplements was observed.That was accompanied by a marked reduction of …
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Effect of Fatty Acid Modification on Prostacyclin Production in Cultured Human Endothelial Cells (Arachidonate, Elcosapentaenoate)
… of radiolabel. Phosphatidylinositol and phosphatidylethanolamine contained intermediate percentages while phosphatidylserine and sphingomyelin contained the least. In a dual label supplementation regimen (150 (mu)M ('14)C-EPA and 16 (mu)M ('3)H-AA), phosphatidylinositol appeared to be …
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Biochemical and Structural Characterization of the Atg8/LC3 Lipidation Pathway
… their covalent ligation to lipids, typically phosphatidylethanolamine (PE), in a process known as lipidation. Lipidation of Atg8 family proteins regulates numerous facets of the autophagy process, including regulating expansion of the phagophore membrane, recruiting selected cargoes for …
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The importance of long chain polyunsaturated fatty acids for fetal immune system maturation and function
… the first study to examine the lipid profile of phosphatidylethanolamine (PE) and phosphatidylcholine (PC) fractions of CBMC membranes from preterm and DNI neonates. The LCPUFA composition of CBMCs was dominated by arachidonic acid (AA, 20:4co6) in the PE (34%) and PC fractions (15%) in term …
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Studies of the idiotypic network through the use of a novel hemolytic plaque assay
… SRBC through a covalently attached dipalmitoyl phosphatidylethanolamine (DPPE) tail. When the Ab2 response following murine immunization with DNP-Ficoll was analyzed using such an assay, peak plaque forming cell (PFC) numbers were found to coincide with peak Ab1 PFC numbers in both the primary …
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The Effect of 48 hr Glucose Administration on the Hepatic P-450 System
… as the phospholipids phosphatidylcholine and phosphatidylethanolamine. Changes in lipid content and specific fatty acid content have been shown to be associated with changes in microsomal P-450 activity and the binding of various substrates to P-450. The data reported in these studies suggest …
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ATG8 Regulation and Function in Non-Canonical Autophagy
… the lipid species conjugated to ATG8 proteins is phosphatidylethanolamine (PE). However, using mass spectrometry, this study shows for the first time in vivo that ATG8 proteins can become conjugated to both PE and phosphatidylserine (PS) upon stimulation of non-canonical autophagy. Furthermore, …
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Lipid metabolism and mitochondrial respiration in adipose tissue and liver during obesity
… in membranes i.e. phosphatidylcholine/phosphatidylethanolamine (PC/PE) ratios in both brown and white adipose tissues. When the effects of sex and obesity were investigated in adipose tissue, a positive correlation was again detected between PC/PE ratio and mitochondrial respiratory …
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Effect of phospholipase C papain on feathering defect in 11% homogenized UHT processed cream
… phosphatidylserine, phosphatidylinositol, and phosphatidylethanolamine) were hydrolyzed by phospholipase C while sphingomyelin remained intact. Heat treatment of whey protein at 80°C for 7 minutes to cover newly formed fat globule did not prevent the feathering problem in papain-treated cream.
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