Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"phosphatidylcholine (PC)"”.
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Phospholipid Transfer From Vesicles to High Density Lipoproteins, Catalyzed by Human Plasma Phospholipid Transfer Protein (Liposome)
… protein (PLTP) catalyzes the mass transfer of phosphatidylcholine (PC). Partial purification of PLTP yielded proteins with apparent M(,r) = 59,000 and 40,000 by SDS-PAGE. PLTP activity was measured by transfer of ('14)C L-(alpha)-dipalmitoyl PC from egg-PC vesicles to HDL. Activity was enhanced …
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Effect of Structure and Composition of Reconstituted High Density Lipoproteins on Phosphatidylcholine Transfer by Human Plasma Phospholipid Transfer Protein
… used to study the effect of HDL substrates on phosphatidylcholine (PC) transfer by human plasma phospholipid transfer protein (PLTP) by changing the composition and size of rHDL. Sonicated egg-PC:cholesterol vesicles containing radiolabelled dipalmitoyl-PC ($\sp $C-DPPC) were used as donors and …
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Characterization of the lipid composition of washed and percoll gradient centrifuged epididymal mouse sperm.
… and the fatty acyl chain compositions of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) were characterized in washed non-capacitated (WS), washed capacitated (WCS), and Percoll gradient centrifuged (PGC) capacitated (PGCS) epididymal mouse sperm. Fatty acid methyl esters were …
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Interactions of Inorganic Mercury and Inorganic Cadmium with Biomimetic and Complex Biological Membranes and their Influence on Membrane Packing and Size
… as a catalyst in the vinyl ether hydrolysis of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) plasmalogens. Cd2+-induced rigidity of anionic membranes results in a stabilization of the gel phase and a suppression of the Tm of membranes composed of phosphatidic acid (PA), cardiolipin …
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The Effect of Seven Carcinogens on Phosphatidylcholine and Phosphatidylethanolamine Metabolism in Larvae of the Indian-Meal Moth
<p>Alterations of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) metabolism were investigated in the larvae of Plodia interouncte11a (Indian-meal moth) receiving diets containing seven different carcinogense The fatty acid composition of PC and PE as well as the radioactive …
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The Saccharomyces cerevisiae phosphatidylinositol/phosphatidylcholine transfer protein functions as a negative feedback regulator of the CDP-choline pathway
… cerevisiae phosphatidylinositol (PI)/phosphatidylcholine (PC) transfer protein (SEC14p) is required for Golgi function in vivo. Mutations that specifically result in the inactivation of the CDP-choline pathway for PC biosynthesis bypass the requirement for SEC14p. The in vivo …
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Synthesis and Evaluation of Trans-bilayer Cross Linking Phospholipids Based on Click (Azide-Alkyne) Chemistry
This thesis describes the synthesis of two phosphatidylcholine (PC) derivatives that are capable of coupling with each other from the alkyl chain through click reaction to form bola-PC. Successful coupling of monomeric phosphatidylcholine derivatives would lead to synthesis of corresponding …
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Novel Metabolic Regulation of Invadopodia and Invasion by Acetyl-CoA Carboxylase and Lipogenesis
… phospholipid profiles, including that of phosphatidylcholine (PC). Exogenous supplementation with fatty acid or PC following ACC inhibition was sufficient to restore both the formation and gelatin-degrading capabilities of invadopodia in 3T3-Src cells. Moreover, the lipid-dependent …
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Molecular and biochemical characterization of phospholipase D in cotton (Gossypium hirsutum L) seedlings.
… characteristic HKxxxxD catalytic domains, a PC-binding domain, a PIP2-binding domain and a C2 domain. In addition both cotton PLD β isoforms had a N-terminal "SPQY" rich domain which appeared to be unique to these PLDs. The three PLD δ isoforms, designated Ghpldδ1a, Ghpldδ1b and Ghpldδ1b-2 …
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The Impact of Dietary Fat and Phosphatidylcholine on Increased Trimethylamine-N-oxide Levels
… to dietary TMA containing substrates such as phosphatidylcholine (PC), choline, and L-carnitine. A high-fat diet is an environmental risk factor that may increase TMAO production. However, it isn’t clear if the high dietary intake of TMA is sufficient to promote increased plasma TMAO or if a …
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Spontaneous Phosphatidylcholine Exchange Between Vesicles and Micellar Lipid-Apolipoprotein Complexes
The spontaneous exchange of phosphatidylcholine (PC) between model lipoproteins and small unilamellar vesicles was investigated. The model lipoproteins were recombinants of bovine apolipoprotein A-I, egg PC, and cholesterol produced by cholate dialysis. Vesicles contained egg PC and cholesterol in …
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Optimizing Faba Bean Protein-Stabilized Cream Emulsions to Develop a Plant-based Whipped Cream
… One phospholipid contained a higher amount of phosphatidylcholine (PC), whereas the other contained a higher amount of phosphatidylinositol (PI). Although both emulsion variations resulted in stable cream emulsions, the addition of PI resulted in the reduction of interfacial tension and …
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The importance of long chain polyunsaturated fatty acids for fetal immune system maturation and function
… profile of phosphatidylethanolamine (PE) and phosphatidylcholine (PC) fractions of CBMC membranes from preterm and DNI neonates. The LCPUFA composition of CBMCs was dominated by arachidonic acid (AA, 20:4co6) in the PE (34%) and PC fractions (15%) in term neonates (>37 weeks, n=9). Compared to …
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Structural effects of neutral lipids on the divalent cation-induced interactions of phosphatidylserine - containing bilayers
… data from multilamellar systems suggest that phosphatidylcholine (PC) and diacylglycerol (DG) might be in the collapsed phase up to a concentration of -30 mole % and that above this concentration these neutral lipids may modify Ca2+-induced bilayer interactions. Using large unilamellar …
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The Ligand and Membrane-binding Behaviour of the Phosphatidylinositol Transfer Proteins (PITPa & PITPb)
… to transfer either phosphatidylinositol (PI) or phosphatidylcholine (PC) between membrane compartments in vitro. In Drosophila, the PITP domain is found to be part of a multi-domain protein named retinal degeneration B (RdgBα). The PITP domain of RdgBα shares 40 % sequence identity with PITPα and …
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Golgi phospholipid composition is a critical determinant of Golgi secretory competence in yeast
… been shown to be the phosphatidylinositol (PI)/phosphatidylcholine (PC) transfer protein of yeast and serves to transport PI and PC monomers between natural or artificial lipid bilayers, in vitro. The stimulation of yeast Golgi function by the Sec14p has further been shown to correlate with the …
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Pct1 regulates phosphatidylcholine synthesis in response to changes in surface curvature elastic stress sensed on the inner nuclear membrane
… found in membranes of living organisms, phosphatidylcholine (PC) is the most abundant. The rate-limiting step of the predominant pathway for PC synthesis in eukaryotic cells is catalysed by the enzyme, CTP: phosphocholine cytidylyltransferase α (CCTα or PCYT1A). CCTα has a critical role …
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Regulation of Highly Unsaturated Fatty Acid Metabolism
… and eritadenine, which increase membrane PE/phosphatidylcholine (PC) ratio, suppress D6D mRNA and activity in rat liver. Therefore, we hypothesized that an increase in membrane PE/PC ratio suppresses D6D gene transcription by down-regulating SREBP-1 activation. Ethanolamine, eritadenine and …
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Determination of the roles of the Trypanosoma brucei lipin homologue TbLpn
… used to form phosphatidylethanolamine (PE) and phosphatidylcholine (PC), which are major lipids that constitute the membrane of T.b. In order to better understand how TbLpn functions, we checked if it was phosphorylated in vivo by protein methyl transferases termed (TbPRMT1 and TbPRMT7) in …
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