Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"phosphate homeostasis"”.
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Investigating the role of phosphate homeostasis in Staphylococcus aureus virulence
… and other important biological processes, phosphate is an essential nutrient for all organisms. Bacteria possess a variety of complex phosphate sensing and uptake systems to ensure that they meet their need for phosphate. The ubiquity and necessity of these systems make them a possible …
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Phosphate homeostasis and posttranscriptional gene regulation during arbuscular mycorrhizal symbiosis in Medicago truncatula
Since available phosphate (Pi) resources in soil are limited, symbiotic interactions between plant roots and arbuscular mycorrhizal (AM) fungi are a widespread strategy to improve plant phosphate nutrition. The repression of AM symbiosis by a high plant Pi-status indicates a link between Pi …
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Phosphate homeostasis and novel microRNAs are involved in the regulation of the arbuscular mycorrhizal symbiosis in Medicago truncatula
Die arbuskuläre Mykorrhiza ist die wahrscheinlich älteste Form der Wurzelsymbiosen zwischen Pflanzen und Pilzen und hat sich vor 420 Millionen Jahren entwickelt. In dieser Symbiose, die zwischen nahezu allen Landpflanzen und Pilzen des Reiches Glomeromycota ausgebildet wird, versorgt der Pilz die …
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Subcloning and regulation of a human intestinal sodium-phosphate cotransporter gene
Phosphate plays a critical role in the body as a constituent of bone and tooth for body development, and as a urinary buffer for pH in body acid-base balance regulation. The phosphorus level in blood in human is between 3.0 to 4.5 mg/dl. When the blood phosphate concentration is lower than 2.5 …
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Molecular Genetic Analysis of FGF23 Bioactivity in the Bone-Kidney Endocrine Axis
Heritable disorders of phosphate handling are the most common cause of hypophosphatemic rickets in developed countries. Isolated renal phosphate wasting and subsequent low serum phosphate concentrations may result from a number of genetic disorders that include: autosomal dominant hypophosphatemic …
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Investigating the impact of phosphate acquisition and homeostasis on staphylococcus aureus pathogenesis
Phosphate is an essential nutrient for all organisms. Therefore, transporters and regulatory systems in bacterial pathogens enabling phosphate acquisition within the host are important for virulence. However, the contribution of phosphate homeostasis to infection by the ubiquitous pathogen …
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Role of the Vitamin D Receptor in Insulin Secretion and Beta Cell Function
… in the islet is klotho, a key regulator of phosphate homeostasis. We clearly establish that klotho mRNA and protein are detected in beta cells of mouse islets, at levels sufficient to mediate signal transduction pathways via klotho’s role as a co-receptor for FGF23. By analysis of islets …
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Uraemic vascular damage and calcification in children with chronic kidney disease
… manifested by hyperparathyroidism and high phosphate, in association with low vitamin D levels, is key to the pathophysiology of ectopic vascular and soft tissue calcification. In addition, a number of treatment- related factors can potentially lead to a high calcium load, contributing to an …
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Elucidating the molecular basis of dihydroxyacetone (DHA) production in Leptospermum nectar
… LmSGPP2 can dephosphorylate dihydroxyacetone-phosphate (DHAP) to produce DHA and phosphate in vitro. Transgenic Petunia and Nicotiana lines were created to characterise LmSGPP2 activity in vivo, but results were inconclusive due to low and mis-located expression of the transgene. Together our …