Global ETD Search
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Showing 1 to 3 of 3 for “"phosphatase substrate"”.
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Towards understanding substrate recruitment by PP1 holophosphatases
… known as kinases and the removal is catalysed by phosphatases. Over 98% of phosphorylation sites on proteins occur on serine and threonine residues and a major serine/threonine phosphatase within the human cell is protein phosphatase 1 (PP1). This enzyme functions as a holoenzyme, with a core …
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The Development of Photo-crosslinkable Trapping Mutants as Tools to Investigate the Interactions of Protein Tyrosine Phosphatases
… in the coordinated activities of protein phosphatases (PPs) and<br/>protein kinases (PKs) contribute to the development of many diseases.<br/>Phosphatase of regenerating liver (PRL)-3 and Vaccinia H1-Related (VHR) are<br/>two members of the protein tyrosine phosphatase (PTP) family shown …
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Mechanisms of polyphosphate degradation
… was that native serum endo- and exopolyphosphatases degraded polyP. To study the degradation of polyP in vivo and identify putative polyphosphatases, we needed to develop a high-throughput method for measuring polyphosphatase activity. The study of polyP long has been hampered by the …