Global ETD Search

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Showing 1 to 2 of 2 for “"phenotypic drug discovery"”.

  1. Creating effective drug discovery methods in Mycobacterium abscessus

    … efficacy is through continued development of new drugs capable of evading resistance mechanisms. However, over the past 30 years the antibiotic drug development space has been characterised by the withdrawal of recourses, large pharmaceutical companies, and funding. This is a result of a mismatch …

    cambridge Repository record for Creating effective drug discovery methods in Mycobacterium abscessus (opens in a new tab)

  2. Development of novel receptor tyrosine kinase inhibitors by a chemocentric approach

    … target. This is referred to as target-based drug discovery. It was hoped that adopting this approach would usher in a new golden age of drug discovery. However, this has not been the case, with issues arising such as the target’s mechanism of action being poorly understood, with it not …

    edinburgh Repository record for Development of novel receptor tyrosine kinase inhibitors by a chemocentric approach (opens in a new tab)