Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"phenothiazinium"”.
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Synthesis of Phenothiazinium Derivatives
… this project we synthesized new derivatives of phenothiazinium for potential applications in PDT. Phenothiazinium was synthesized and derivatized by linking it to side groups containing imidazole rings. These derivatives are also expected to catalyze certain hydrolytic reactions. Such ôhydrolase …
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Synthesis and electrochemistry of photoantimicrobial agents based on the azine chromophore
… stains methylene blue and toluidine blue 0, both phenothiazinium derivatives, have been widely studied with respect to their use in PDT and potential antimicrobial applications. However, studies of novel methylene blue derivatives (MBD) for PDT are scarce in the literature. We have synthesised a …
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Investigation into the toxicity and DNA interactive properties of a range of cationic photosensitisers with potential application to photodynamic antimicrobial chemotherapy
… study, the therapeutic potential of a series of phenothiazinium-based photo-sensitisers (PhBP5) to act as novel antibacterial agents is investigated. It is shown that these PhBPs possess maximal light adsorption characteristics (A), which range from 536 nm - 648 nm, a characteristic, …
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Use of tissue culture to investigate the effect of methylation on methylene blue cytotoxicity
… the photocytotoxicity and dark toxicity of the phenothiazinium dyes, methylene blue and toluidine blue-O, against the mammary tumour cell line, EMT-6. The toxicities of the dyes and several derivatives were assayed using standard tissue culture techniques and the …
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Investigation into the toxicity and membrane interactive properties of a range of cationic photosensitisers with potential application to Photoantimicrobial Chemotherapy
… study, the therapeutic potential of a series of phenothiazinium based photosensitisers (PhBPs) to act as novel photodynamic antibacterial agents is investigated. It is shown that Azure A, Azure B, Azure C, Brilliant Cresy! Blue, Neutral Red, Pyronin Y, To!uidine Blue 0, New Methylene B!ue and …
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Investigation into the potential of methylene blue and its derivatives to be used in the photodynamic therapy of non-pigmented and pigmented cells
… application of the current work, PDT employing phenothiazinium photosensitizers is not suggested procedurally for the removal of primary melanoma, since this is routinely performed by excision. However, due to the demonstrated efficacy of MB in tracing microsatellites and its use in sentinel …