Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"pharyngitis"”.
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A meta-analysis of interventions to increase adherence to medication regimens for pediatric otitis media and streptococcal pharyngitis
Interventions to increase adherence to medication regimens for acute pediatric illnesses are important for both individual and public health outcomes. To date, there has not been a comprehensive, quantitative analysis of the effectiveness of interventions for acute pediatric illnesses. The current …
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An Epidemiological Evaluation of Antagonism Between the Normal Throat Flora and Group a Streptococci
… and prevention of group A streptococcal pharyngitis and its sequela of rheumatic fever have been extensively studied. Estimates of the incidence of streptococcal pharyngitis in the United States have ranged from 400,000 to 7 million cases annually. Case rates are highest in the winter and …
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Phenotypic and Genotypic Models of Streptococcal Colonization of the Human Tonsil
<p>Pharyngitis due to oropharyngeal infection with Streptococcus pyogenes is most commonly treated by using penicillin-derived antibiotics.While treatment failure in the 1950's was reported in 4-8% of children, more recent studies have alarmingly found antibiotic failure as high as 20-40% providing …
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Antibacterial peptides - key players in host defense at epithelial surfaces
… has an affinity for epithelial cells and cause pharyngitis. During streptococcal pharyngitis, high concentrations of the chemokines CXCL9/MIG, CXCL10/IP-10, CXCL11/I-TAC were found in tonsil fluid. Similarly, these chemokines were produced by activated pharyngeal epithelial cells in vitro. …
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Streptococcal virulence and the coagulation system.
… of host plasminogen–in conditions simulating pharyngitis, a very common superficial streptococcal infection. Pharyngitis is characterized by the exudation of plasma into an environment with saliva. We find that saliva affects the initiating enzymes of the intrinsic pathway of coagulation, and …
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A study of determinants and prevalence of Rheumatic Heart Disease in Cape Town
… a continued high prevalence of GAS-positive pharyngitis and RHD. Furthermore, while much is known about the social factors and the microbial agent that predispose individuals to ARF, little progress has been made in elucidating genetic susceptibility factors that are reproducible in different …
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Turning Tears into Sweets: CandyCollect for Pediatric Salivary Pathogen Sampling
… diagnosed with Group A Streptococcus (GAS) pharyngitis. In summary, this dissertation spans from the foundational design principles of open microfluidic systems to their practical application in enhancing human pathogen sampling.
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Antibiotikų skyrimo ypatumai suaugusiems, sergantiems kvėpavimo takų infekcijomis, pirminės sveikatos priežiūros įstaigose Lietuvoje /
… acute viral respiratory tract infection (41,5%), pharyngitis (28,9%) among URTIs and acute bronchitis (52,1 %) among LRTIs. Prevalence of RTIs was higher in private centers (74,1%0 than in polyclinics (36,0%) (p<0,001). Prevalence of RTIs among males and females was similar (53,0% and 55,1%). …
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Streptococcal colonization of host mucosal surfaces: a study of biofilm formation and dispersal
… a variety of human diseases. Infections include pharyngitis, otitis media, sepsis, a toxic-shock syndrome, necrotizing fasciitis, and the post-infectious sequelae acute rheumatic fever and acute rheumatic heart disease. Thus, rather than exploit a singular niche, GAS has evolved to colonize and …
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Prevalence and environmental risk factors for ten zoonoses in two cree communities of James Bay (Canada
… and for F. tularensis in cases of strong pharyngitis. The effects of zoonotic diseases are marginal compared to the benefits of maintaining a traditional diet and preserving a feeling of connectedness to traditions and culture.
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Antibiotikų vartojimo ypatumai 2003 - 2008 m. Lietuvoje /
… for one of the most frequent infection acute pharyngitis / tonsillitis might be improved by implementation of rapid antigen detection tests. The extent of antibiotic consumption in nursing hospitals is low, but it is uncontrolled. Therefore the development of correct population approach, …
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AFROStrep (SA): a surveillance system for group A streptococcal infection in South Africa
… AND DISCUSSION: The pooled prevalence of GAS pharyngitis in Africa was determined to be 21% (95% CI, 17% to 26%). The incidence rates of laboratory-confirmed non-invasive GAS infection in the South African public sector appears to have declined over the last 13 years. Given the possibility …
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The prevalence of Group A Beta-Hemolytic Streptococci carriage in children in Africa: a systematic review
… providers in diagnosing symptomatic GAS pharyngitis, as well as could potentially contribute to the development of a GAS vaccine. Currently, data on GAS carriage prevalence and M-type distribution in African countries are largely scant. We therefore undertook to perform a systematic …
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Use of an Animal Model of Group A Streptococcal Infection to Identify Factors Important for Virulence
… for a broad assortment of diseases ranging from pharyngitis (strep throat) and impetigo to necrotizing fasciitis (flesh eating disease) and streptococcal toxic shock syndrome (STSS). Virulence of the GAS is multifactorial, as it possesses an array of virulence factors regulated in a coordinated …
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Induction of myosin cross-reactive antibody and cytolytic T cell responses in mice with Streptococcus pyogenes
Impetigo and pharyngitis are two common suppurative infections in man elicited by Streptococcus pyogenes that lead to autoimmune complications in susceptible individuals. Although the underlying mechanisms for the onset of post-streptococcal autoimmunity have yet to be established, experimental …
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Protein FOG at the interface between G streptococci and human host defence lines
… are part of the normal flora, but can cause pharyngitis, erysipelas and impetigo. In the immunocompromised host severe conditions, such as sepsis and necrotising fasciitis, may develop. In this thesis the interactions between GGS and various parts of human defence lines are investigated. A …
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CcpA-Mediated Carbon Catabolite Repression of Virulence in the Group A Streptoccus
… ranging from the self-limiting diseases such as pharyngitis and impetigo to the more severe invasive disease such as necrotizing fasciitis. The coordinate expression of a wide array of virulence factors in response to the changing host environment represents a key step in the ability of the GAS …
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Genomic insights into Group A Streptococcus pathogenesis
… The sequela of an untreated or undertreated GAS pharyngitis include Rheumatic Fever (RF) and Rheumatic Heart Disease (RHD). Despite evidence for the effectiveness of antibiotics such as penicillin, the burden of GAS remains high in low- and middle-income countries (LMICs) compared to high-income …
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Transcriptional Regulation of the MGA Virulence Regulon in Streptococcus Pyogenes
… of causing an array of diseases ranging from pharyngitis (strep throat) to necrotizing faciitis (flesh-eating disease). The GAS possesses a transcriptional regulator called Mga, or the multiple gene regulator of the GAS, that responds to growth phase and environmental signals to activate …
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Novel innate immune functions of saliva
… of pathogenic streptococci. Streptococcal pharyngitis is defined by plasma exudation into a saliva rich environment. We found that upon intermixing with plasma, saliva triggers several proteolytic cascades within plasma that include the complement system and both arms of the coagulation …
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