Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"pharmacological resistance"”.
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MOLECULAR MECHANISMS UNDERLYING CLINICAL BEHAVIOR OF NEUROENDOCRINE TUMORS: STUDY OF NEW POSSIBLE BIOMARKERS PREDICTABLE OF PHARMACOLOGICAL RESISTANCE AND TARGETS
… due to recurrence and metastasis accompanied by pharmacological resistance. In this scenario, the lack of effective pharmacological approaches is making hard the treatment of these pathologies. Within the pharmacological context, lot of attention was given to somatostatin and dopamine system, …
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Structure-Function Analysis of Insect Olfactory Receptors
… in a ligand-binding OR subunit leads to pharmacological resistance to the repellent in vivo. This is the first finding that identifies a molecular target of DEET. Within the OR complex, OR83b plays an essential role. Ligand-binding subunits fail to localize properly at the OSN dendrite in …
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Response to treatment with chemical and biological inhibitors of c-met mutated form
… to investigate the mechanisms responsible for resistance, (iii) to check if the resistant mutants are still sensitive to other chemicals inhibitors or monoclonal antibodies against MET, (iv) to identify activating point mutations in human surgically resected lung cancers. We have found that …