Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"pharmaceutical technology"”.
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Hot-melt extrusion: A versatile pharmaceutical technology
Hot-melt extrusion (HME) is a promising technology for the production of new chemical entities in the developmental pipeline and for improving products already on the market. The first objective of this research work was to describe a continuous process for the production of solid lipid …
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A Series of Pharmaceutical Technology Concepts Applied to Pediatric Formulations
… are needed. In response, formulators in the pharmaceutical industry have made significant effort into developing various pediatric formulations. However, developing satisfactory pediatric formulations is a process that is guided by case by case basis. The objective of this current study was …
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Studium tabletovin a tablet s retardující složkou obsahující hypromelosu a sodnou sůl karmelosy.
… of Pharmacy in Hradec Králové Department: Pharmaceutical Technology Student: Kristýna Koukolová Consultant: Assoc. Prof. PharmDr. Jitka Mužíková, Ph.D. Title of the Diploma Thesis: A study of tableting materials and tablets with the retarding component containing hypromellose and carmellose …
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Kultivace kožních štěpů jako modelů pro výzkum bariérové funkce kůže
… of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Supervisor: PharmDr. Anna Paraskevopoulou, Ph.D. Author: Petra Kašparová Title of the thesis: Human skin explants as models for research of skin barrier functions The skin protects the human organism from harmful …
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Emulsão : uma revisão bibliográfica
… unstable systems. Although an ancient pharmaceutical form, emulsions are an area in great research and development. What in the last 20 years has been to prominence and had high acceptability in the pharmacological area, mainly at cosmetology .This paper aims to bring together a …
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Closing the loop : improving technology transfer by learning from the past
Technology transfer is a significant challenge within the highly regulated pharmaceutical industry. While much focus is put on the logistics and strategy of the process, less attention has been paid to how to change the soft, non-technical aspects of technology transfer program management, even …
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Development and Intratumoral Distribution of Block Copolymer Micelles as Nanomedicines for the Targeted Delivery of Chemotherapy to Solid Tumors
Recent advancements in pharmaceutical technology based on principles of nanotechnology, polymer chemistry, and biomedical engineering have resulted in the creation of novel drug delivery systems with the potential to revolutionize current strategies in cancer chemotherapy. In oncology, realization …
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Application of pharmaceutical technologies to improve the activity of cancer chemotherapeutic agents
… quality of life. In this dissertation, different pharmaceutical technology approaches, including nanotechnology and pharmaceutical chemistry, were utilized to improve the activity of chemotherapeutic agents. Docetaxel is a second generation taxane used as a single agent in breast cancer, non-small …
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STUDY OF SOLUBLE OR BIODEGRADABLE DEVICES FOR PROLONGED DRUG DELIVERY IN HOLLOW ORGANS
… delivery systems (DDS) is strictly connected to pharmaceutical technology used for their production, also this research area was deepened with a particular attention to innovative techniques such as 3D or 4D printing. For what concerns urinary bladder, a prototype of a DDS able to be administered …
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Mechanistic studies to evaluate the targeting specificity of novel RGD Micelles to the αVβ3 integrin receptor
<p>Current chemotherapeutics pose many di sadvantages due to their lack of specificity and low therapeutic index. To overcome these challenges, research has focused its attention on the development of nano-based delivery systems that can penetrate the leaky vasculature of tumor endothelium, use …
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Development of dissolving and hydrogel-forming microneedles for delivery of vancomycin hydrochloride
… transdermal drug delivery is microneedle (MN) technology. MN is micron-sized needles on a solid backing or support that can easily penetrate the skin’s stratum corneum barrier, accessing the viable epidermis and dermis. This thesis aimed to investigate the development of dissolving and …