Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"pharmaceutical powder"”.
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Towards real-time understanding of processes in pharmaceutical powder technology
… processes and new ideas to develop traditional pharmaceutical powder manufacturing procedures. Process analytical technology (PAT) has been developed to improve understanding of the processes and establish methods to monitor and control processes. The interest is in maintaining and even …
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Condition monitoring of pharmaceutical powder compression during tabletting using acoustic emission
… system for the final production quality of pharmaceutical tablets and detection capping and lamination during powder compression process using the acoustic emission (AE) method. Pharmaceutical tablet manufacturers obliged by regulatory bodies to test the tablet's physical properties such as …
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Theoretical and experimental investigation of particle interactions in pharmaceutical powder blending
In pharmaceutical manufacturing practices, blending of active pharmaceutical ingredient (API) with excipients is a crucial step in that homogeneity of active ingredient after blending is a key issue for the quality assurance of final products. Inadequate knowledge of the interdependence between raw …
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A STUDY OF COMPRESSION DIE DESIGN ON THE COMPACTION OF PHARMACEUTICAL POWDER
Tablet quality can be affected by feed material, process parameters, equipment configuration and tooling design. Tableting die is part of the compaction tooling and determines tablet size and shape. Dies with modified designs could potentially address tablet compaction issues, such as low tensile …
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Multi-scale analysis and simulation of powder blending in pharmaceutical manufacturing
… out for gaining fundamental understanding of the pharmaceutical powder blending process. Through experiment, analysis and computer simulations, microscopic particle properties were successfully linked to their macroscopic process performance. This work established this micro-to-macro approach as a …
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Process systems engineering of continuous pharmaceutical manufacturing
… number of operational and financial benefits to pharmaceutical companies. This research examines the critical blending step for continuous pharmaceutical manufacturing and the characteristics of continuous downstream pharmaceutical manufacturing systems. Discrete element method (DEM) simulations …
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On the Compaction of Granular Matter; Continuum and Discrete Numerical Modelling
… from assemblies of large rocks to the finest of powders. Nonetheless, compared to fluids and solids, our understanding of granular materials remains limited, because the macroscopic mechanical behaviour of a granular material strongly depends on the interplay between the mechanical properties and …
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Effect of dry particle coating on the properties of cohesive pharmaceutical powders
… of industrial applications, in this case the pharmaceutical industry. This work investigates the effect of dry particle coating to improve the flowability of cohesive active pharmaceutical ingredient (API) powders and their blends. Improving the flow properties of cohesive API powders can …