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Showing 1 to 4 of 4 for “"phagolysosome fusion"”.

  1. Survival Of Mycobacterium Avium Subspecies Paratuberculosis In The Pol

    … Tuberculosis', suggesting the ability to resist phagolysosome fusion, by maintaining association with the early endosomes. Overall, the data confirms map virulence in host human blood leukocytes.

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  2. Analysing M. avium-macrophage interactions and establishing a long-term infection in a novel and realistic model of lung alveolar macrophages, Max Planck Institute Cells

    … responses via mechanisms such as preventing phagolysosome fusion and acidification which allows it to proliferate intracellularly thus assisting MAC in the spread of infection. It is vital that these mechanisms are investigated so that the disease process is better understood, and therapeutic …

    plymouth Repository record for Analysing M. avium-macrophage interactions and establishing a long-term infection in a novel and realistic model of lung alveolar macrophages, Max Planck Institute Cells (opens in a new tab)

  3. Understanding buruli ulcer : elucidation of the cellular and molecular mechanisms underlying infection with mycobacterium ulcerans

    … by IFN-γ, such as phagosome maturation, phagolysosome fusion, and generation of reactive nitrogen intermediates. This inhibition of macrophage antimicrobial activity was due to the production of mycolactone, since the addition of increasing concentrations of purified toxin to cultured …

    minho-thes Repository record for Understanding buruli ulcer : elucidation of the cellular and molecular mechanisms underlying infection with mycobacterium ulcerans (opens in a new tab)

  4. Role of Bacterial Effectors SopD and SopB in Pathogenicity of Salmonella enterica serovar Typhimurium.

    … we have observed that SopB also inhibits fusion of lysosomes with Salmonella-containing vacuoles (SCVs) following invasion. This ability depends on SopB-mediated reduction of negative membrane charge of the SCV during invasion by hydrolysis of the phosphoinositide PI(4,5)P2. Membrane …

    toronto-retro Repository record for Role of Bacterial Effectors SopD and SopB in Pathogenicity of Salmonella enterica serovar Typhimurium. (opens in a new tab)