Global ETD Search
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Showing 1 to 1 of 1 for “"phagocytosis checkpoint"”.
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Atr-Mediated Cd47 and Pd-L1 Upregulation Restricts Radiotherapy-Induced Immune Priming and Abscopal Responses In Colorectal Cancer
… as knockout animals lose most benefit of phagocytosis checkpoint blockade. Despite activation across the myeloid stroma, enhanced dendritic cell function accounts for most improvements in CD8 T cell priming. These data suggest ATR-mediated CD47 and PD-L1 upregulation as a key mechanism …