Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"personalized therapy"”.
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Deep Learning for Enhancing Precision Medicine
… and hence the potential to be translated into personalized therapy. However, the attempts to transform omics data-driven insights into clinically actionable models for individual patients have been limited. Meanwhile, advances in deep learning, one of the most promising branches of artificial …
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Fighting cancer with nanomedicine−drug-polyester nanoconjugates for targeted cancer therapy
… and facilitate targeted cancer diagnosis and therapy. By uniquely integrating well-established chemical reaction-controlled ring opening polymerization (ROP) with nanoprecipitation technique, I successfully developed a polymeric NC system based on poly(lactic acid) and …
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Integrative Analysis of Omics Data In Adult Glioma and Other Tcga Cancers to Guide Precision Medicine
… or prediction of therapeutic response towards personalized therapy for cancer patients. Thanks to modern genome-wide profiling technology, scientists are able to build engines leveraging massive genomic variations and integrating with clinical data to identify “at risk” individuals for the sake …
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Graph Theory and Dynamic Programming Framework for Automated Segmentation of Ophthalmic Imaging Biomarkers
… outcomes for ocular disease patients through personalized therapy.</p>
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AI Assisted Cellular and 3D Spheroid Analyses for Combined Therapies Against Glioblastoma
… survival of only 15 months despite maximal therapy. While combination therapies involving radiation with immunotherapies, epigenetic therapies, molecularly targeted therapies, etc., show promise, current methods for evaluating whether combination therapies work are slow, need extensive …
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Electrodeless electro hydrodynamic printing of personalized drug dosages
… observations have given rise to the concept of personalized therapy whose ultimate goal is to develop medicinal agents designed for each niche of the population and individual patients according to their genetic background. The drawback in current pharmaceutical technologies is that most …
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Accurate Mutation Annotation and Functional Prediction Enhance The Applicability of -Omics Data In Precision Medicine
… management and therefore achieve the goals of personalized therapy. However, the accuracy of large scale sequencing data in clinics has been constrained by many different aspects, such as clinical detection, annotation and interpretation of the variants that are observed in clinical sequencing …
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PRINTING MUCOADHESIVE AND ORODISPERSIBLE FILMS FOR THE PERSONALIZATION OF THERAPY
… for the on-demand point-of-care preparation of personalized dosage forms, since they are simple processes that only require a desktop 3D printer and can potentially be carried out in a pharmacy setting. The aim of this PhD project is therefore to demonstrate the suitability of such techniques …