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Showing 1 to 1 of 1 for “"permissive cleavage"”.
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Mechanism of Permissive Cleavage Activity of TevCas12a
… degrading the substrate. We call this activity permissive cleavage. TevCas12a activity is guide RNA dependent, but not guide RNA sequence specific, it can degrade any DNA substrate with a non-targeted guide RNA. Sequencing of the TevCas12a cleavage products with Oxford Nanopore revealed that …