Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 77 for “"peripheral neuropathy"”.
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Peripheral neuropathy in hypertension
… pressure and may show evidence of subclinical peripheral neuropathy. Hypertension is strongly associated with diabetic neuropathy and the observed sensory loss may be aggravated by hypertension-induced nerve ischaemia and hypoxia. Two studies are presented in this thesis. First, 20 …
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PARESTHESIA DUE TO PERIPHERAL NEUROPATHY: ANXIETY AND WELLBEING
… Tissue compression is the most common cause of peripheral neuropathy (PN) as well as paresthesia. This study aimed to test the following hypotheses: (1) if paresthesia due to PN is positively correlated with anxiety, negatively correlated with wellbeing, and if (2) anxiety and (3) wellbeing …
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Mechanisms of Astrocyte Contribution to Bortezomib-Induced Peripheral Neuropathy
… frequently accompanied by chemotherapy-induced peripheral neuropathy (CIPN) that may be dose-limiting, adversely affecting quality of life and prognosis. The mechanisms behind bortezomib-induced peripheral neuropathy (BIPN) and CIPN overall are largely unknown. Recent findings in other pain …
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Genetics of hearing impairment and peripheral neuropathy in Mali
… disease (CMT), is the most common inherited peripheral neuropathy (IPN) with a high clinical and genetic heterogeneity and over 100 genes are related to CMT, mostly in populations of Caucasian ancestry. Yet, despite being described more than 130 years ago, there remains a paucity of …
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The Effects of a Novel Therapeutic Intervention in Diabetic Peripheral Neuropathy Patients
… The most common complication of DM is diabetic peripheral neuropathy. Diabetic peripheral neuropathy causes reduced sensation, reflexes, proprioception, and strength in lower limbs that leads to balance problems. Various manual therapy techniques have not approached a pilot study for the …
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Kratom Alkaloid Mitragynine: Therapeutic Role and Potential Utility Against Chemotherapy-Induced Peripheral Neuropathy
… pain conditions, chemotherapy-induced peripheral neuropathy (CIPN) persists as a monumental public health crisis, as it is the most common comorbidity among those receiving chemotherapy for cancer treatment. CIPN is unique compared to other forms of neuropathic pain in that it is …
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The Role Of Adult Stem Cells And Tumor Necrosis Factor In Peripheral Neuropathy
<p>Peripheral neuropathies are a significant cause of morbidity and mortality, with a population prevalence of 2,400 per 100,000 (2.4%) that increases in the elderly to 8,000 per 100,000 (8%)(C. N. Martyn and R. A. Hughes, 1997). The variations in symptom distribution and etiologic attribution have …
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Implementation of Novel Group Delay Decomposition Method and Surgical Protocol for Assessing Peripheral Neuropathy
<p>This paper outlines a surgical procedure for exposing and stimulating the sciatic nerve of an anesthetized rodent for purposes of obtaining conduction velocity readings. The ability to accurately quantify nerve conduction velocity has potential for use in the field of diagnostic medicine and …
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Development of a mobile-enabled vibration perception threshold device to screen for peripheral neuropathy
… complication of diabetes is distal symmetric polyneuropathy (DSPN), which is nerve damage that typically leads to a loss of tactile sensation in the feet and is a major cause of foot ulcers and leg amputations. A key limitation to current screening and ulcer prevention in India is the …
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Neurochemical characterization of primary sensory neurons in a rat model of bortezomic-induced peripheral neuropathy
Peripheral neuropathies, as the result of nerve damage, are characterized by pain, numbness, and tingling in the extremities and slow nerve conduction. Chemotherapy-induced peripheral neuropathy is a major dose-limiting side effect of many other commonly used chemotherapeutic agents, including …
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Peripheral neuropathy and depressive symptomology : examining the association among persons with and without diabetes mellitus.
Peripheral neuropathy (PN) symptoms among the general population are underappreciated. Physical symptoms of PN are known to significantly increase the risk of disability. However, less is known about the mental health impact that symptoms of PN have, especially among populations traditionally …
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Gamification of Exercise and Its Application for Fall Prevention Among Patients with Diabetes and Peripheral Neuropathy
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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The effects of peripheral nerve impairments on postural control and mobility among people with peripheral neuropathy
Approximately 20 million Americans are suffering Peripheral Neuropathy (PN). It is estimated that the prevalence of all-cause PN is about 2.4% in the entire adult population, whereas over 8-10% in the population segment over the age of 55 (Martyn & Hughes, 1997). Peripheral Neuropathy leads to a …
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Peripheral neuropathy and quality of life of adults living with HIV/AIDS in Rulindo District in Rwanda
Peripheral neuropathy (PN) is a common neurological complication occurring in the asymptomatic and symptomatic stages of human immune deficiency virus (HIV) infection. The pain and other symptoms caused by PN can impair functional ability and limit physical activity that could affect quality of …
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The Impact of Type 2 Diabetes and Associated Diabetic Peripheral Neuropathy on Grip Force Control and Hand Function
… type 2 diabetes (T2D) and associated diabetic peripheral neuropathy (DPN). This might impact their ability to perform essential tasks such as buttoning a shirt, picking up pills, and monitoring blood sugar. Understanding the nature of such deficits is of utmost importance. This dissertation …
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Investigation of chemotherapy-induced peripheral neuropathy-related behaviour in male and female ratsa role for the endocannabinoid system
Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and debilitating side effect of cancer treatment, often persisting for months after therapy cessation and profoundly impairing quality of life. Among chemotherapeutic agents, paclitaxel (PTX) stands out for its broad clinical use …
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THE USE OF PREVENTATIVE CANNABIDIOL, CANNABIGEROL, AND MITRAGYNINE TO AMELIORATE MECHANICAL SENSITIVITY OF PACLITAXEL-INDUCED PERIPHERAL NEUROPATHY IN FEMALE MICE
Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling side effect of cytotoxic chemotherapy drugs. It has been reported that >60% of patients receiving chemotherapy suffer from this debilitating condition, which manifests itself in a polyneuropathy of paresthesia, hyperalgesia, …
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Insoles to ease plantar pressure in people with diabetes and peripheral neuropathy: a feasibility randomised controlled study with embedded qualitative component
… plantar pressure in people with diabetes and peripheral neuropathy: a feasibility randomised controlled study with embedded qualitative component. Background: Diabetic foot ulceration is a devastating complication of diabetic foot disease. Therapeutic footwear and insoles are one preventative …
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