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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 41 for “"peripheral arterial disease"”.
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Peripheral Arterial Disease from Aetiology to Surgical Management
… with a group<br/>of papers focused on aneurysmal disease, specifically, abdominal aortic aneurysms (AAA), the clinical impact of which has had a bearing on the introduction of a National AAA Screening Program in Wales in 2013.<br/><br/>I conclude these sections with a collection of papers that …
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Peripheral Arterial Disease Screening of an Underserved High Risk Population
… often present with increased risks for peripheral arterial disease. Some patients with peripheral arterial disease are asymptomatic and may defer treatment while others present with occlusive disease requiring immediate therapy. Delaying diagnosis and treatment reduces quality of life …
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Non-contrast Magnetic Resonance Angiography for Evaluation of Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a major cause of morbidity and mortality in the USA with an estimated prevalence of up to 20% in those over 75 years. Vascular disease and kidney impairment frequently coexist; prevalence of moderate to severe renal dysfunction in PAD patients is estimated at …
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Multimodal imaging monitoring of key physiological changes of peripheral arterial disease
Peripheral Arterial Disease (PAD) limits blood flow to the lower extremities, causes functional impairment, and in extreme cases, can lead to amputation. While PAD is widely studied, there is still a large gap between preclinical research and clinical translation. This is due in part to the lack of …
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A comparative study of home based exercise on symptomatic peripheral arterial disease
Peripheral arterial disease (PAD) is a prevalent atherosclerotic disorder characterised by exertional limb pain, loss of limb and a high mortality rate - those patients with an ABPI of<0.40 have a 5-year probability of survival of only 44%. Intermittent claudication, the exercise-induced ischaemic …
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Allopurinol as a possible oxygen sparing agent during exercise in peripheral arterial disease
Patients with peripheral arterial disease (PAD) can only walk so far before they get leg pain (intermittent claudication) and have to stop. They are also at risk in the future of needing amputation of one of their limbs. Allopurinol is a new possible treatment for this condition as it has been …
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Methodology for quantitative assessment of perfusion in porcine model of peripheral arterial disease
Peripheral artery disease (PAD) is the degradation of perfusion in the lower muscles caused by the narrowing of upstream arteries. Currently, the diagnosis and prognosis of the disease rely almost entirely on hemodynamic metrics of major vessels affecting the periphery. Quantitative assessment of …
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Novel Treatment of Anal Fistulas and Endovascular Drug Delivery for Peripheral Arterial Disease
ABSTRACT #1: Peripheral Arterial Disease Drug Delivery Peripheral arterial disease affects 6.5 million people over the age of 40 in the USA. This blood circulation disorder blocks peripheral arterial blood vessels, restricting oxygen-rich blood flow to the limbs and increasing chances of limb loss. …
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A multimodal lens into vascular recovery in a preclinical model of peripheral arterial disease
… factors is disrupted, either through injury or disease. Cardiovascular complications are among the leading causes of morbidity and mortality in diabetic patients, and account for over 80\% of diabetes-associated deaths. One of the most serious is peripheral arterial disease (PAD), which is …
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Prevalence of left ventricular hypertrophy in peripheral arterial disease and its relation to blood pressure
… (LVH) inpatients with newly diagnosed peripheral arterial disease (PAD).<br/><br/>Methods: Consecutive patients referred for the first time for assessment of PAD with a history of intermittent claudication and ankle brachial pressure of index of ≤0.9 were recruited. All subjects …
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Peripheral arterial disease and diabetes: effects on endothelial progenitor cell differentiation and nitric oxide metabolism
In the recent years it is emerged that peripheral arterial disease (PAD) has become a growing health problem in Western countries. This is a progressive manifestation of atherothrombotic vascular disease, which results into the narrowing of the blood vessels of the lower limbs and, as final …
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Vascular calcification as a risk factor for peripheral arterial disease and its effects on angiogenesis
Peripheral arterial disease (PAD) refers to the obstruction or blockage of arteries of the lower extremity vessels. PAD is characterised by accelerated arterial calcification and impairment in angiogenesis, both of which associate with adverse cardiovascular outcomes. The pathogenesis of lower …
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A contemporary examination of screening for peripheral arterial disease for the purpose of cardiovascular risk assessment
Peripheral Arterial Disease (PAD) is a marker of systemic atherosclerosis and is associated with a three to six fold increased risk of death from cardiovascular causes. Furthermore, it is typically asymptomatic and under-diagnosed; this has resulted in escalating calls for the instigation of …
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Does nursing expertise contribute to the accuracy of vascular assessment in the detection of peripheral arterial disease?
… basis for diagnosing the presence or absence of arterial occlusive disease in the legs. Seventy-six nursing participants with a variety of experience—novice n = 14, advanced beginner n = 22, competent n = 12, proficient n = 16, and expert n = 12—performed arterial assessments prior and after …
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Metabolic profile and post-operative outcomes in contemporary patients with peripheral arterial disease and critical limb ischaemia
Background: Peripheral arterial disease (PAD) is an established occlusive disease of the peripheral arteries and is not uncommon in the elderly. Atherosclerosis accounts for 90% of the pathology. Only 15% of affected individuals become symptomatic. Most symptomatic individuals present with …
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Pattern and distribution of peripheral arterial disease in diabetic patients with critical limb ischemia (Rutherford Clinical Category 4-6)
… suffer from tibio-peroneal artery occlusive disease (1) (2) (11) (5) (10) (8) with relative sparing of the foot arteries (1). This study seeks to investigate the pattern and distribution of peripheral artery occlusive disease and the arterial foot arch status in diabetic patients with …
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Use of a tourniquet in lower limb amputations: Evaluating blood loss in peripheral arterial disease patients A systematic review
… as an adjunct in lower limbs amputation in peripheral arterial disease to reduce blood loss and requirement for blood transfusions. Stump revision rate, complication and mortality will be assessed as secondary objectives. Method: For this systematic review, a search was performed using the …
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Association of baseline sex hormone levels and prevalent and incident peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis
Peripheral arterial disease (PAD) is a progressive disease that affects up to 10% of the population worldwide. The burden of this disease on individuals, health systems, and communities remains high and will likely only increase as our population continues to age. While treatment and prevention …
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Mathematical Models of Major Arterial Occlusion
… modeling to investigate the effects of major arterial occlusion in multiple tissues and vascular geometries. A network representing the vasculature of the rat hindlimb is used to study peripheral arterial disease characterized by femoral artery occlusion. This work couples responses that occur …
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Multi-modality Imaging to Determine the Role of Calcification and Inflammation on Restenosis Rates Following Lower Limb Angioplasty
Peripheral arterial disease (PAD) is a major cause of CVD-related death and disability. Restenosis is common, occurring in 40-60% of cases at 12 months following lower extremity percutaneous transluminal angioplasty (PTA). No such method exists to identify patients who are at risk from restenosis …
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