Global ETD Search
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Showing 1 to 2 of 2 for “"pericentrin"”.
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CHARACTERISATION OF A NOVEL SPINDLE DOMAIN IN MAMMALIAN MEIOSIS
… with the essential aMTOC component, Pericentrin. In the absence of PCM1, aMTOCs could no longer assemble or maintain their structural integrity. PCM1 degradation and disassembly of aMTOCs disrupted spindle assembly and reduced the total amount of nucleated microtubules throughout …
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Vascular Disease Pathogenesis In Smooth Muscle Dysfunction Syndrome and Majewski Osteodysplastic Primordial Dwarfism Type Ii
… disease in MOPDII using a novel SMC-specific pericentrin knock-out mouse line (<em>Pcnt<sup>SMKO</sup></em>). Using this mouse model, we identify increased proliferation of SMCs explanted from the aortas of <em>Pcnt<sup>SMKO</sup></em> mice and activation of the ataxia telangiectasia and rad3 …