Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"pericardium"”.
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A description of the pharmacokinetics of first line anti-tuberculosis drugs and adjunctive corticosteroid therapy in the pericardial compartment and their effect on cytokine profiles in the pericardial compartment of patients with tuberculous pericarditis
… by Mycobacterium tuberculosis infection of the pericardium, which is associated with a higher mortality, compared with pulmonary tuberculosis. Constrictive pericarditis, a significant complication of tuberculous pericarditis, contributes to this elevated mortality. Adjunctive corticosteroid …
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A novel polymeric prosthetic heart valve: design, manufacture, and testing
… worse than expanded polytetrafluoroethylene and pericardium graft materials. In measures of inflammation, the BCPs and polytetrafluoroethylene were better than polyester and pericardium. A durable heparin coating gave SEPS22 superior haemocompatibility compared to all the reference materials. The …
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Reduction of post-surgical pericardial adhesions using a pig model
… polyethyleneglycol (Co-Seal) was applied to the pericardium as a barrier in Group four. After performing a median sternotomy, an adhesion induction model was applied to maximize inflammation in the pericardium. This included abrasion of the heart surface, leaving blood in the pericardium and …
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Immunological analysis of pericardial tuberculosis
… novel insight into the immune response in the pericardium to TB infection. Furthermore, HIV-1 infection caused a dysregulation of the immune response.
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Biomechanical structure-function relationships of collagen tissues, B Cell membranes, and amyloid fibers
… collagen tissues such as ligaments, tendons, and pericardium that serve as load bearing components in biological systems. A novel micromechanical model describing the force-extension of wavy fibers comprising these tissues is integrated with bundle and network frameworks. The developed models …
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Ex-vivo-Expansion perikardialer Patchstrukturen : zur Frage des Einflusses von zyklischem Stress und laminaren Strömungsbedingungen auf das Ex-vivo-Remodelling perikardialer Patchstrukturen
BACKGROUND: Pericardium is widely used as a patch structure in paediatric cardiovascular heart surgery. However, the major problem still is the restricted availability and level of quality of autologous pericardium. Based on those limiting factors, a new concept has already been tested in a pilot …
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Fully Coupled Fluid Structure Interaction Simulation of Bioprosthetic Heart Valves: A Numerical and Experimental Analysis
… Previous computational studies assumed (bovine pericardium) BP used in BHVs density was comparable to water or blood. Yet, BP is subjected to multiple treatments like fixation and anti-calcification. In Chapter 2, I measured BP density and its effect on BHV leaflet stress and strain. In the …
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Surgical techniques used for closure of perimembranous ventricular septal defects
… (n=71). Five patients in Group I had bovine pericardium used and 1 patient's VSD was closed by a direct suture technique. Group II consisted of 93 children operated on between 1995 to 1998, and had their VSDs closed with a 0.6% glutaraldehyde-treated autologous pericardial patch using 5.0 …
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The tetrapeptide Ac-SDKP and angiotensin converting enzyme in tuberculous pericarditis and fibrosis
… the metabolism of AcSDKP in the tuberculous pericardium. Ac-SDKP levels as measured by ELISA, were significantly decreased (2.3 fold) in TB pericardial fluid as compared to controls. This reduction in Ac-SDKP levels was accompanied by a local 28% increase in the enzymatic activity of ACE, but …
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Untersuchung der Kalzifikation von Perikard und Polyurethan in Abhängigkeit des pH-Wertes
… of Calcification. Incubation of PUR and bovine pericardium using buffered physiological fluid to precipitate is carried out. With 0.024 M HEPES-and TRIS buffer solution bovine plasma was adjusted to the pH-values 7.0, 7.2, 7.4, 7.6, 7.8 in which varying PUR and glutaraldehyd-preserved bovine …
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Performance characteristics of the left ventricle during and following induced extrasystoles
… function of the heart in dogs with the chest and pericardium open, and under strictly controlled conditions. In spite of all the work j done in this field, there still exists some degree of confusion regarding the relative importance of autoregulatory mechanisms and extrinsic factors governing …
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Paravalvular sealing pf percutaneous heart valves
… (THV's) rely on sealing skirts made from treated pericardium or polyethylene terephthalate (PET) fabrics. The current study was aimed at developing novel electrospun skirts for the minimization of PVR in THV's. Thermoplastic polyurethane (TPU) was electrospun onto mandrels and several techniques …
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Cells of the Developing Human Heart and Great Vessels
… and the great vessels. Chapter 6 explores the pericardium and endocardium as the two layers enveloping the myocardium. Ultimately, through the profiling obtained from the atlas, Chapter 7 proposes a framework to generate enhanced stem cell models to mimic the corresponding cells *in vivo*.
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Reduction of Myocardial Stunning by in Situ Genetic Alteration of Myocytes
… heart. Therefore pMTSOD was injected into the pericardium with the expectation that cytoplasmic SOD levels would be elevated resulting in an increased resistance to reperfusion injury. Two days following intrapericardial injection of the plasmid, hearts were subjected to ischemia and …
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Fatigue life modelling of anisotropic styrenic block copolymers for a prosthetic heart valve application
… were significantly lower than on bovine pericardium, which is one of the materials used in clinical prosthesis. Durability of the calcified valve was not affected, indicating that the selected materials have great potential for biomedical applications. Finally, the effect of heparin …
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Investigating the pathways involved in the progression of fibrosis in tuberculous pericarditis
… (TBP) is a severe form of EPTB involving the pericardium that is present in 1-2% of TB cases, and poses diagnostic and therapeutic challenges, with mortality rates ranging between 8-34% despite anti- tuberculous therapy. TBP is the leading cause of pericardial constriction in Africa which is a …
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Role of macrophages in larval zebrafish heart regeneration
… macrophages to be recruited first from the pericardium and then the caudal haematopoietic tissue, preferentially using the abluminal wall of blood vessels to migrate to the site of injury. I next used macrophage-less irf8-/- larvae and metronidazole-nitroreductase macrophage ablation to test …
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