Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"peptide vaccination"”.
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Intranasal Hpv Peptide Vaccine Formulation Induces Potent Cytotoxic Cd8 T Cell Immunity For The Treatment of Genital Hpv Tumors
… cancers are textbook candidates for therapeutic vaccination intervention because they’re driven by the expression of viral oncoproteins E6 and E7, which serve as ideal tumor specific antigen targets. An effective therapeutic vaccine should be able to overcome tumor mechanisms of immune-evasion …
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Memory Potential, Molecular Characterization, and Translational Applications of The Novel Theo/Tceo T Cell Phenotype
… Anti-4-1BB antibodies synergize with HPV peptide vaccination to eradicate HPV+ murine tumors, due to a honed tumor-specific ThEO response. Further, ThEO phenotype cells infiltrate the livers of α4-1BB treated mice, which may play a role in 4-1BB mediated hepatotoxicity. Finally, we show …
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Importance of specific NK cell subsets for antitumor immunity in HPV+ cancers
… the DC marker CD11c, via therapeutic HPV peptide vaccination, contribute to tumor-free long-term survival.</p> <p>In addition to antigen-specific CD8 T cell responses, overall innate immune effector responses, including polyfunctional NKDC, were elevated in mice treated with and HPV …
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Identifikation und immunologische Charakterisierung von MHC-Klasse-II-Peptidepitopen in humanen Leukämie- und Lymphom-assoziierten Antigenen
… Hauptziel dieser Arbeit war es, MHC Klasse-II Peptidepitope in den Proteinen zu identifizieren, welche eine tumor-assoziierte Expression aufweisen und die bereits bekannte Zielantigene von zytotoxischen T-Zellreaktionen sind. In dieser Arbeit wurden die Proteine Proteinase 3 (PR3) und Survivin …