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Showing 1 to 1 of 1 for “"peptide staples"”.
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A Survey of Stapling Methods to Increase the Affinity, Activity and Stability of Ghrelin Analogues
… can be overcome by incorporating helix-inducing staples that stabilize its structure and improve affinity and activity. We present an analysis of different stapling methods at positions 12 and 16 of ghrelin(1-20) analogues with the goal of increasing proteolytic stability and to retain or improve …