Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"peptide linkers"”.
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Luminescent Quantum dots for Cellular Analysis
… to the surface of the quantum dots through peptide linkers, which contained selective enzymatic cleavage sites. Upon enzymatic cleavage of the peptide linkers, the rhodamine molecules no longer provided an efficient energy transfer channel to the quantum dots, which brightened the previously …
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An alum particle-based platform to enhance and investigate humoral immune responses to immunization
… In this thesis, we investigate the use of peptide linkers containing consecutive phosphoserine residues (pSer) designed to mediate ligand exchange interactions between pSer- conjugated antigens and aluminum hydroxide (alum) particles in order to mediate slow delivery of antigen from the …
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Nanoparticle coatings for spatial and temporal control of cancer imaging and therapy
… vectors using electrostatically adsorbed peptide linkers, enabling localized gene delivery to cancer cells expressing tumor-associated proteases. 4) Electrostatic coatings for gene delivery vectors are characterized and developed in vivo, leading to the identification of certain …
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Mutations Within and Between Early Cell Division Proteins and Their Effects On Division Regulation In Escherichia Coli
… tolerant of large deletions in their flexible linkers between their respective FtsZ-binding domains and membrane-associated domains. In particular, I found that the deletion of the proline/glutamine-rich domain in the ZipA linker enhances ZipA’s resistance to toxic FtsA overexpression, …
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Enzymatic crosslinking of dynamic hydrogels for in vitro cell culture
… reversible stiffening through SrtA-mediated peptide ligation were established. Specifically, poly(ethylene glycol) (PEG)-peptide hydrogels were fabricated with peptide linkers containing pendent SrtA substrates. The hydrogels were stiffened through incubation with SrtA, whereas gel softening …