Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"pentose sugars"”.
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Metabolic engineering of Saccharomyces cerevisiae for efficient ethanol production from pentose sugars
… from lignocellulosic feedstock. Unfortunately, pentose sugars, which constitute up to 30% of biomass hydrolysate, cannot be utilized by S. cerevisiae. To this end, heterologous pentose utilization pathways have been introduced into S. cerevisiae in order to enable the assimilation of pentose …
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Discovery and characterization of pentose-specific transporters in Saccharomyces cerevisiae
… from lignocellulosic feedstock. Unfortunately, pentose sugars, which make up to 30% of lignocellulose, cannot be utilized by S. cerevisiae. Pentoses can only enter yeast cells through hexose transporters, which have two orders of magnitude lower affinities for pentose sugars. Additionally, …
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Optimizing pentose sugar utilization in Escherichia coli for the production of biofuels
… and xylose. Effective metabolism of all sugars in biomass by a microorganism is regarded as essential for commercial biofuel production. However, two of the major challenges that we are currently faced with are the transport of sugars into the microorganism and the co-utilization of these …
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Regulation of Hexose and Pentose Metabolism by Escherichia Coli
… in order to selectively process individual sugars. By identifying the mechanism for this control, I have identified specific genetic targets for subsequent metabolic engineering. This discovery will enable the construction of E. coli strains capable of simultaneously and efficiently …
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A New Method for the Analysis of Carbohydrates by Means of Vanillin in Acid Medium
Sugars have probably been looked upon with more interest than any other class of organic compounds. From the analytical standpoint there has been an abundant amount of excellent work. Brown and Zerban (l) mention that the analysis of sugars with phenols and hydrochloric acid frequently offers a …
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Fermentative utilization of glycerol and lignocellulosic sugars and production of ethanol by Paenibacillus macerans
… glycerol fermentation in P. macerans. Hexose and pentose sugars make the largest portion of lignocellulosic biomass, which is the ideal substrate for the production of biofuels. Most microorganisms can not utilize hexose and pentose sugars simultaneously. In this study, we have shown that P. …
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Strain engineering and biosensor development for efficient biofuel production by Saccharomyces cerevisiae
… strains capable of converting glucose or pentose sugars into ethanol. Unfortunately, pentose sugars, which constitute up to 30% of biomass hydrolysate, cannot be co-utilized simultaneously with glucose by recombinant S. cerevisiae strains. Great efforts have been made to improve the …
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Improved xylose fermentation by expression of a putative xylose transporter encoding gene HXT2.4 in Saccharomyces cerevisiae
… S. cerevisiae cannot consume xylose, a pentose sugar which comprises almost 30% of lignocellulosic biomass. Metabolic and genetic engineering methods were used to develop S. cerevisiae that could consume xylose. However in S. cerevisiae, pentose sugars can only enter the cell through …
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Isolation, Characterization, and Synthesis of Bioactive Natural Products from Rainforest Flora
… characterized the derivatized, hydrolyzed sugars. Previous investigations of Albizia subdimidiata provided two saponins including the new compound albiziatrioside A. The sugar moieties of these two compounds required further characterization. They were characterized by spectral analysis of …
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Engineering Zymomonas mobilis for efficient fuel ethanol production from lignocellulosic feedstocks
… has been engineered to ferment all of the sugars present in cellulosic biomass, but the digestion of five carbon sugars by the strain is still slow and inefficient. The inefficiencies are present because Z. mobilis displays preferential sugar digestion—only after all six carbon sugars in …
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Characterization and engineering of sugar transporters in the yeast Kluyveromyces marxianus for biotechnological applications
… requires the simultaneous consumption of all the sugars present in this raw material, hexoses and pentoses. This represents a key bottleneck because of the low number of specific pentose transporters identified and the slow rate of pentose uptake into the yeast cell when glucose is present. …
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Optimal yeast strains for the production of fuels and chemicals from lignocellulosic biomass
… biomass, however, contains both hexose and pentose sugars, mainly glucose and xylose, which are not efficiently fermented by microbes. Despite numerous efforts for improving xylose fermentation during the last two decades, a method for engineering efficient xylose-fermenting strains has not …
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Engineering a Fungal L-Arabinose Pathway Towards the Co-Utilization of Hemicellulosic Sugars for Production of Xylitol
… of desired product. Xylitol is an attractive pentose sugar alcohol that has many applications in the food, pharmaceutical, and high-value based biochemical product industries. It is still, however, relatively expensive to produce, which prevents its economical integration into the marketplace. …
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Engineering a Fungal L-Arabinose Pathway Towards the Co-Utilization of Hemicellulosic Sugars for Production of Xylitol
… of desired product. Xylitol is an attractive pentose sugar alcohol that has many applications in the food, pharmaceutical, and high-value based biochemical product industries. It is still, however, relatively expensive to produce, which prevents its economical integration into the marketplace. …
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Novel Cellular Targets of Aspirin in Chemoprevention studies on P53, G6PD and c-MYC
… of DNA and RNA through the production of pentose sugars. c-Myc is a transcription factor (TF), which is mutated and constitutively activated in 20% of all cancers. The studies on p53 and G6PD are an extension of the previous work carried out in our laboratory, in which we demonstrated the …
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Engineering Zymomonas mobilis for the production of biofuels and other value-added products
… it can efficiently produce ethanol from simple sugars using unique metabolic pathways. Z. mobilis displays what is known as the “uncoupled growth” phenomenon, meaning cells will rapidly convert sugars to ethanol regardless of their energy requirements for growth. This makes Z. mobilis attractive …
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Characterization of Extremophilic Bacteria for Potential in the Biofuel and Bioprocess Industries
… compounds with inhibitory effects on growth and pentose sugars released after hydrolysis. Polyhydroxyalkanoates (PHA) are bio-plastics produced by some bacteria. There is interest in industry in the identification of bacteria that can utilize wastes from some bioprocesses while creating …
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Innovative Methods for Biomass Sugars Utilization
… as ethanol and furans) requires both hexose and pentose sugars released to be fully utilized to make this process cost-effective. However, the efficient xylose utilization through either fermentation or chemical conversion is the cost-limiting step. First, the major challenge for using xylose for …
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Optically pure D (-) lactic acid biosynthesis from diverse renewable biomass: microbial strain development and bioprocess analysis
… and cost effectiveness compared to refined sugars and cereal grain-based sugars. Commercial use of lignocellulosic biomass for economic production of lactic acid requires microorganisms that are capable of using all sugars derived from lignocellulosic biomass. Therefore, the objectives of …
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Techno-economic analysis and environmental assessment of isobutene, sustainable aviation fuel, omega-3 and omega-6 oils, and sophorolipid production in integrated sugarcane biorefineries
… to the ability of the microorganism to utilize pentose sugars. Economic viability was determined through a discounted cash flow rate of return analysis to calculate minimum selling prices (MSPs) for an acceptable return on investment, which were compared to prevailing market prices. Life cycle …