Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"pediatric glioma"”.
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Comprehensive Analysis of the Molecular Underpinnings of Pediatric Glioma
… tumors affecting children. Of these CNS tumors, gliomas are the most prevalent. Currently gliomas are histologically segregated into two umbrella categories: low-grade glioma (grades 1 and 2, pLGG) and high-grade glioma (grade 3 and 4, pHGG). pLGG are the most frequently diagnosed pediatric …
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Targeting Unique Domains of Lsd1 Regulates Pediatric Glioma Innate Immunity and Nk Cell Metabolism
… may aid new modalities such as immunotherapy. Pediatric high-grade gliomas (pHGGs) often possess mutations in histone coding genes that cause aberrant histone methylation and gene expression. Cells derived from these patient’s tumors display growth inhibitory sensitivity to epigenetic drugs …
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Dynamic Contrast-Enhanced MR Microscopy: Functional Imaging in Preclinical Models of Cancer
… of the blood-brain barrier in a mouse model of pediatric glioma and for identifying regions of therapeutic effect in a model of colorectal adenocarcinoma. </p><p>It is shown that 4D radial keyhole imaging does not degrade the system spatial and temporal resolution at a cost of 20-40% decrease in …