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Showing 1 to 3 of 3 for “"pdh1"”.
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Novel Determinants That Influence Azole Susceptibility in Candida glabrata and Candida albicans
… the multidrug resistance transporters Cdr1, Pdh1, and Snq2. However, the specific relative contribution of these transporters to resistance is not known. In order to determine this, the <em>SAT</em><em>1 </em>flipper method was used to delete <em>CDR1</em>, <em>PDH1</em>, and <em>SNQ2 </em>in …
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Transcriptional Regulation of Azole Antifungal Resistance and Tolerance in Candida Glabrata
… transporter genes <em>CgCDR1</em> and <em>CgPDH1</em>. It was previously reported that azole-resistant mutants (MIC ≥ 64 μg/ml) of strain 66032 (MIC = 16 μg/ml) similarly show coordinate <em>CDR1</em>-<em>PDH1</em> upregulation, and in one of these (F15) a putative gain-of-function mutation …
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Breeding Euphorbia lagascae for large-scale production of vernolic acid, an important industrial epoxidized ester
Euphorbia lagascae is grown because of vernolic acid, an epoxidized fatty acid that has multiple industrial uses. The objective of this thesis was to determine the genetic control of seed germination and seed shattering traits. Five different wild-type genotypes of E. lagascae that demonstrated …