Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"pattern separation"”.
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Pattern Separation in the Ventral Visual Stream
Pattern separation is a neural computation thought to underlie our ability to form distinct memories of similar events. It involves transforming overlapping inputs into less overlapping outputs. In the ventral visual stream (VVS) there is considerable evidence for hierarchical transformation from …
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Linear and ellipsoidal pattern separation: theoretical aspects and experimental analysis
This thesis deals with a pattern classification problem, which geometrically implies data separation in some Euclidean feature space. The task is to infer a classifier (a separating surface) from a set or sequence of observations. This classifier would later be used to discern observations of …
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Mismatch Negativity as a Marker of Auditory Pattern Separation Integrity in Aging
… Findings reinforce the MMN as a marker of pattern separation integrity, and clarify how age-related declines in mnemonic discrimination are explained by age differences at encoding.
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Pattern separation abilities are selectively related to food label and numeracy nutrition skills
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-05-01
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Disambiguating the Similar: Investigating Pattern Separation in Medial Temporal Lobe Structures Using Rodent Models
… investigates the mechanisms underlying pattern separation, using rodent models and behavioural tasks that assess the use of representations for similar stimuli. Pattern separation is a theoretical mechanism involving the transformation of inputs into output representations that are less …
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Effect of Epigallocatechin-3-gallate on a pattern separation task and hippocampal neurogenesis in a mouse model of Down syndrome
… study investigated deficits in a radial arm maze pattern separation task in Ts65Dn mice. Pattern separation requires differentiation between similar memories acquired during learning episodes; distinguishing between these similar memories is thought to depend on distinctive encoding in the …
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Cognitive Health in Black and Latina Midlife Women: The Role of Sleep and Vasomotor Symptoms
… Verbal Learning Test–II (CVLT-II) and a pattern separation task sensitive to hippocampal subfield function. Results: Sleep disturbance was not significantly associated with cognitive performance. However, a greater frequency of VMS during sleep—though not across 24 hours—was significantly …
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Non-motor symptoms in the aav-α-synuclein rat model of Parkinson’s disease: exercise as a therapeutic intervention
… of AAV-αsynuclein induced distinct patterns of nigrostriatal degeneration and associated motor dysfunction. Overexpression of AAV-α-synuclein was used to model NMS associated with PD, including deficits in hippocampalassociated tasks. This was coupled with α-synuclein-positive …
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Effects of Memorability on Mnemonic Discrimination
… across memory for similar events. Hippocampal pattern separation permits the differentiation between similar experiences, while pattern completion allows for the reconstruction of experiences from partial cues. However, these hippocampal computations have yet to be examined in the context of …
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Tracking The Flow of Information Through The Hippocampal Formation In The Rat
… two competitive, yet complementary, processes. Pattern separation, hypothesized to occur in the dentate gyrus (DG), refers to the ability to decrease the similarity among incoming information by producing output patterns that overlap less than the inputs. In contrast, pattern completion, …
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An optimization approach to relate neural circuit architecture, loss landscapes and learning performance in static and dynamic tasks
… architecture and match the circuit’s structural patterns to its behavior. One pattern of notable importance that we observe throughout the brain is dimensionality expansions, whereby a small population of neurons diverge onto a large group of neurons with synapses that convey the same …
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Firewall-Architekturen für Multimedia-Applikationen
… firewall architecture has to apply the design pattern "Separation of Signalling and Media Flows". A new architectural model is introduced which can be used to structure firewall architectures regarding the criterias necessary to support multimedia applications. Thus, it is possible to …
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Cardiorespiratory fitness as a modulator of hippocampal subfield structure and function in cognitive aging
… Accurate episodic memory formation requires pattern separation, a neurocomputational process that orthogonalizes similar stimulus input into distinct neural representations and can be examined using behavioral mnemonic discrimination paradigms in humans. Age-related impairment in …
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The medial prefrontal cortex and the dorsomedial striatum are necessary for working memory in rats: role of NMDA receptors
… concurrent assessment of delay-dependent and “pattern separation” effects that were not possible with previous delayed-non-match-to-sample-tasks. The odour span task (OST) measures working memory capacity using an incremental delayed-non-match-to-sample paradigm that involves the addition of …
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Behavioural and neural dynamics of category learning across the menstrual cycle
… a separate cognitive task that relies on similar pattern separation processes as category learning and further demonstrates the utility of the method developed in Study 1. Study 4 (N=64) takes the analysis a step further by examining hormone-gene interactions in participants tested twice, at low- …
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An Investigation into the Mechanisms Underlying Mnemonic Precision
… imagery. Specifically, we examined perceptual pattern completion, the process that enables us to recognize an entire object from a partial stimulus, and asked if this process is differentially impacted by visual disruption in aphantasics. We find that while aphantasics have intact pattern …
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Using Multimodal MRI Techniques to Understand the Role of Hippocampus in Schizophrenia
… functions in dentate gyrus could decrease its pattern separation function. Multimodal MRI techniques including proton magnetic resonance spectroscopy (1H-MRS), cerebral blood volume (CBV), cerebral blood flow (CBF) and functional MRI at 3T were used to examine the metaplasticity model and probe …
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Peripheral alterations underlying the negative effects of a cafeteria diet on brain and behaviour: exercise as a mitigating strategy
… forms of memory, including spatial memory and pattern separation, and in regulating emotion through anxiety behaviours and antidepressant action. A cafeteria (CAF) diet, mimicking human Western-style diets, has been shown to decrease AHN, impair memory, and increase anxiety-like behaviour in …