Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"patient-derived organoid"”.
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Investigating circuit and spatial heterogeneity of human brain tumors with patient-derived organoid models
… to unravel GBM heterogeneity by leveraging patient-derived GBM organoids (GBOs), a 3-dimensional model inspired by human brain organoids. In the first sections of this dissertation, I describe the application of circuit neuroscience techniques to study diverse tumor-neuron circuitry. …
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PATIENT-DERIVED ORGANOIDS AND EXTRACELLULAR VESICLES: UNLOCKING NEW FRONTIERS IN BREAST CANCER DRUG TESTING AND BIOMARKER DISCOVERY
… BC are not satisfactorily tailored to individual patients and often result in failure. The main reason of that is tumor heterogeneity, resulting in different levels of aggressiveness and treatment sensitivity. To address this challenge, personalized medicine strategies are crucial; achieving this …