Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"patient responses"”.
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Proteomic studies on patient responses to chemotherapy, radiotherapy and immunotherapy in cancers
… study of primary and secondary autoimmune responses of various cohorts of cancer patients prior to and/or following a variety of distinct treatments (chemotherapy, radiotherapy and immunotherapy), using a large number of archived human serum samples. Our goals were to develop and validate a …
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Analyzing factors affecting patient satisfaction using the Kano model
… advancements, rising costs, and shifts in patient demographics. Challenges associated with understanding patient needs impact the quality of care and life, safety, and satisfaction. The objective of this research was to develop a methodology to collect and analyze the needs associated with …
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Patient Experiences with the New Nurse Practitioner Role in New Brunswick Canada
… interpretive description study was to examine patient responses to this new role of NP in New Brunswick. Purposeful sampling was used to recruit 17 participants who were patients of eight NPs who had practiced in New Brunswick for at least a year. Data were collected by interviews and …
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Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array
… to assay the serological response of cancer patients to at set of selected cancer testis antigens in order to infer a diagnosis value or to assess the patient responses to particular treatments. However, the acquisition of the array data is subject to bias and noise. Therefore, array data …
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The feasibility of a mental practice protocol for severe upper extremity hemiparesis
… of following a MP protocol in the acute inpatient rehabilitation setting. Design: single-group, pretest-posttest Setting: acute inpatient rehabilitation Subjects: 11 patients, less than 1-month post-stroke with severe UE hemiparesis and 17 occupational therapists working in acute inpatient …
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Optimizing the neural response to electrical stimulation and exploring new applications of neurostimulation
… stimulation has been successful in treating patients who suffer from neurologic and neuropsychiatric disorders that are resistant to standard treatments. For deep brain stimulation (DBS), its official approved use has been limited to mainly motor disorders, such as Parkinson's disease and …
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AXL Targeting Restores PD-1 Blockade Sensitivity of STK11/LKB1 Mutant NSCLC Through Expansion of TCF1+ CD8 T Cells
… lung cancer (NSCLC) are associated with poor patient responses to immune checkpoint blockade (ICB) for unknown reasons. We found that introduction of a Stk11/Lkb1 (L) mutation into murine lung adenocarcinomas driven by mutant Kras and Trp53 (KP) resulted in an ICB refractory syngeneic KPL …
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Domestic violence against women and the impact of routine screening in a hospital emergency department
… staff in the B, or screening phase, documented patient responses to screening, as well as barriers perceived to prohibit screening. Requests for referral from the Emergency department to the hospital Social Work department were totalled in a period preceeding routine screening, and during the …
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Training 6th year medical students in the use of supportive communication strategies in obtaining a case history from adults with aphasia : preliminary findings
… the first point of contact between doctors and patients. For patients who have suffered a stroke, this interaction is often a frustrating attempt to tell the doctor how they are feeling and a struggle on the part of the doctor, to obtain the necessary facts. In this study, a group of 6th year …
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Physiological Responses in OSA Patients to Ramping Exercise After CPAP Treatment
… during a ramped exercise. The five male, OSA patients had mean values and standard deviations for RDI=60.7 +/- 19.1, BMI=29.9 +/- 2.9, and age=56 +/- 16.1 yr. Subjects were examined before and after 4 wk of CPAP therapy. After 4 wk of CPAP therapy, patient responses to exercise showed a 17.6%, …
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Patient’s perception of cancer-related depression/anxiety during their treatment
<p>Patients with cancer are emotionally affected during their cancer treatment course. Sometimes, patient’s psychological issues are overlooked during the actual disease treatment. Cancer patients are at a higher risk of developing anxiety and depression (A&D). A presumptive diagnosis of anxiety …
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Explanatory models of illness amongst primary health care users in Mamre
… explores the illness experiences of twenty one patients who presented for treatment at primary health care settings in Mamre, a small "coloured" community approximately 50km from Cape Town, with the aim of investigating the possible contribution of psychological factors to presentation for …
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Mathematical Modelling of Immuno-Oncology and Related Immunology
… allows it to fight cancer without overwhelming patients with potentially fatal inflammatory toxicity has yet to be solved. This partly results from lingering unanswered questions in immunology and partly results from the inevitable variability between one patient and the next. Here we look …
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The Victim-Patient’s Search for Redress: Evaluating Responses to Patient Safety Incidents in Nigeria
Patient Safety Incidents (PSIs) remain a pressing global concern, significantly impacting patient outcomes, healthcare quality, and the overall welfare of populations. Despite advancements in medical science and technology, the occurrence of preventable harm in healthcare settings continues to pose …
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Biological, Clinical, and Functional Implications of Cell-Free DNA Topology in Cancer
… it contains actionable information about a patient’s disease and can be readily obtained via a simple blood draw. In addition to its use in biomarker applications, cfDNA may also function as a mediator of pro-inflammatory signaling in the tumour microenvironment. Despite its mounting …
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Development of micro fluidic based devices for studying tumour biology and evaluating treatment response in head and neck cancer biopsies
… provides a new platform for testing individual patient responses to chemotherapy, paving the way for ‘personalised’ treatment regimens.
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A Systems Approach to Modelling Tumour and Tissue Response in Radiotherapy for Head-and-Neck Cancer
The heterogeneity of patient responses to radiotherapy poses significant challenges in head-and-neck cancer (HNC), with outcomes ranging from severe toxicities to loco-regional recurrence (LRR). Multi-modal biomarker data—encompassing genetic, dosimetric, and imaging domains—offers an opportunity …
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Investigating functions of tumor-infiltrating natural killer cells in genetically-engineered mouse models of non-small cell lung cancer
… on understanding the factors that dictate patient responses to immunotherapy, for the identification of possible points of intervention to expand the fraction of patients who benefit from therapy. The majority of approved immunotherapeutics directly target adaptive immune effectors. …
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Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment
… in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. Knowledge about the predicted course of the disease, sociodemographic and clinical factors affecting the outcome and the impact of ChEI …
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A Signal to Divide: Apoptotic Extracellular Vesicles as Carriers of Mitogenic and Immunogenic Signals
… of biomarkers to specifically detect and monitor patient responses to chemotherapy.</p>
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